- This drug may rarely cause swollen liver and an acid health problem in the blood. This may be deadly in some cases. The chance may be higher in women, in overweight people, and in people who have taken drugs like this one for a long time. Talk with your doctor.
- Hepatitis B has gotten worse when this drug was stopped in some people with hepatitis B. Close follow-up for a few months is needed when therapy is stopped in people who have hepatitis B. Do not stop taking this drug without calling your doctor. Talk with your doctor.
- It is used to treat HIV infection.
- It is used to treat hepatitis B infection.
- If you have an allergy to tenofovir or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are taking another drug that has the same drug in it.
- If you are taking adefovir.
- If you are taking any drugs that can raise the chance of kidney problems. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If you are breast-feeding. Do not breast-feed while you take this drug.
For all patients taking this drug:
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Bone problems like bone pain, soft bones, and thin bones have happened with this drug. This may lead to broken bones. You may need to have a test to check your bones. Talk with your doctor.
- Take calcium and vitamin D as you were told by your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
Treating HIV infection:
- This drug is not a cure for HIV. Stay under the care of your doctor.
- Hepatitis B or C testing may be done. A hepatitis B or C infection may get worse during care. Talk with the doctor.
- If giving to your child, the dose of this drug may need to be changed as your child’s weight changes. Have your child’s weight checked often. Talk with the doctor before changing your child’s dose.
- This drug is not a cure for hepatitis infection. Stay under the care of your doctor.
- You will need to have an HIV test as you were told by your doctor. Talk with your doctor.
For all patients taking this drug:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps.
- Low mood (depression).
- Bone pain.
- Muscle pain or weakness.
- Pain in arms or legs.
- Change in body fat.
Treating HIV infection:
- This drug may help the immune system work. If you have an infection that you did not know you had, it may show up when you take this drug. Tell your doctor right away if you notice any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after you start this drug.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Feeling tired or weak.
- Trouble sleeping.
- Take this drug at the same time of day.
- It is important that you do not miss or skip a dose of this drug during treatment.
- Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
- Take with or without food. Take with food if it causes an upset stomach.
- Wash your hands before and after use.
- Use only the scoop that comes with the powder to measure powder.
- Mix powder with 2 to 4 ounces (60 to 120 mL) of a soft food like applesauce, baby food, or yogurt. Swallow right away without chewing. Chewing the food may make it taste very bad.
- Do not mix with any liquid.
- Wash and dry the scoop after each use. Do not store it in the bottle.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
- Store in the original container at room temperature.
- Keep lid tightly closed.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.