- Rare reports of bleeding into the brain have happened. Harm to the liver has also happened. Sometimes these side effects have been deadly. Patients with hepatitis B or C may have more chance of liver problems. Talk with the doctor.
- It is used to treat HIV infection.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child is not taking ritonavir.
- If your child has liver disease.
- If your child takes any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for high cholesterol, migraines, or mood problems. There are many drugs that must not be taken with this drug.
- Do not give St. John’s wort with this drug. This drug may not work as well.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- This drug interacts with many other drugs. The chance of this drug’s side effects may be raised or how well this drugs works may be lowered. The chance of the other drugs’ side effects may also be raised. This may include very bad, life-threatening, or deadly side effects. Check with your doctor and pharmacist to make sure that it is safe for your child to take this drug with all of their other drugs (prescription or OTC, natural products, vitamins).
- If your child has high blood sugar (diabetes), talk with the doctor. This drug can raise blood sugar.
- Some people with hemophilia have had times of more bleeding when taking drugs like this one. If your child has hemophilia, talk with the doctor.
- Have your child’s blood work checked often. Talk with your child’s doctor.
- This drug is not a cure for HIV. Be sure your child stays under the care of the doctor.
- Your child may get sunburned more easily. Avoid lots of sun, sunlamps, and tanning beds. Use sunscreen and dress your child in clothing and eyewear that protects him/her from the sun.
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood. Be sure needles and other things like toothbrushes or razors are not shared. Talk with the doctor.
- Use with care in children. Talk with the doctor.
If your child is or may be sexually active:
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through having sex. Be sure your child does not have any kind of sex without using a latex or polyurethane condom. Talk with the doctor.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Be sure your child uses some other kind of birth control also like a condom when taking this drug.
If your child is pregnant or breast-feeding a baby:
- Tell the doctor if your child is pregnant or becomes pregnant. You will need to talk about the benefits and risks of your child using this drug while pregnant.
- Be sure your child does not breast-feed a baby if she has HIV disease unless the doctor tells her to.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
- Very bad belly pain.
- Very upset stomach or throwing up.
- Very bad headache.
- Any bruising or bleeding.
- Feeling very tired or weak.
- Not able to pass urine or change in how much urine is passed.
- A fast heartbeat.
- Flu-like signs.
- Muscle or joint pain.
- Numbness and tingling.
- Shortness of breath.
- Change in body fat.
- This drug may help the immune system work. If your child has an infection that you did not know was there, it may show up when your child takes this drug. Tell your child’s doctor right away if you see any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after your child starts this drug.
- Loose stools (diarrhea).
- Feeling tired or weak.
- Belly pain.
- Upset stomach or throwing up.
- To gain the most benefit, do not miss giving your child doses.
- Give as you have been told, even if your child feels well.
- This drug must be taken with another drug called ritonavir. If your child takes ritonavir capsules or liquid (solution), give this drug with or without meals. If your child takes ritonavir tablets, give this drug with meals.
- Do not give didanosine within 2 hours of this drug.
- Have your child swallow whole. Do not let your child chew, break, or crush.
- Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.
- Talk with the doctor before you give your child other sources of vitamin E. This drug has vitamin E in it.
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Store unopened containers in a refrigerator. Do not freeze.
- After opening, store at room temperature.
- Store at room temperature. Do not refrigerate or freeze.
- After opening, throw away any part not used after 60 days.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.