Bethkis; Kitabis Pak; Tobi; Tobi Podhaler
JAMP-Tobramycin; TOBI; TOBI Podhaler; Tobramycin For Injection; Tobramycin For Injection, USP; Tobramycin Injection; Tobramycin Injection, USP
- Very bad kidney problems, nerve problems, hearing problems, and hearing loss may happen with this drug. Other very bad problems like eyesight problems, trouble keeping your balance, and brain problems may also happen. Sometimes these effects do not go away. The risk is much greater in people who already have kidney problems. Tell your doctor if you have kidney problems. Your doctor will watch you closely and may run hearing or kidney tests. The risk may also be higher in older patients, infants, or patients who have fluid loss. Talk with the doctor.
- Do not use this drug if you are taking or have recently taken any drugs that can cause nerve, kidney, or hearing problems. This may be drugs like amphotericin B, bacitracin, cephaloridine, cisplatin, colistin, cyclosporine, ethacrynic acid, furosemide, paromomycin, polymyxin B, vancomycin, viomycin, or other drugs like this one. There are many other drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- This drug may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking this drug, call your doctor right away.
- It is used to treat bacterial infections.
- If you have an allergy to tobramycin or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are taking any of these drugs: Ethacrynic acid, furosemide, mannitol, or urea.
- Tell dentists, surgeons, and other doctors that you use this drug.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have a hearing test before starting this drug and then every year.
- Do not use longer than you have been told. A second infection may happen.
- If you are 65 or older, use this drug with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- If you are allergic to sulfites, talk with your doctor. Some products have sulfites.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in the amount of urine passed, blood in the urine, or a big weight gain.
- Change in balance.
- Very bad dizziness or passing out.
- Fever or chills.
- Sore throat.
- Muscle pain or weakness.
- A burning, numbness, or tingling feeling that is not normal.
- Ringing in the ears, hearing loss, or any other changes in hearing.
- Cough that does not go away.
- Coughing up blood.
- Any bruising or bleeding.
- Feeling very tired or weak.
- Change in thinking clearly and with logic.
- It is common to have diarrhea when taking this drug. Rarely, a very bad form of diarrhea called Clostridium difficile (C diff)–associated diarrhea (CDAD) may occur. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen while you are taking this drug or within a few months after you stop taking it. Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Change in taste.
- Change in voice.
- Loose stools (diarrhea).
- Upset stomach or throwing up.
- Pain where the shot was given.
- To gain the most benefit, do not miss doses.
- Use as you have been told, even if you feel well.
Liquid for breathing in:
- You will use by breathing in from the mouth with a special machine (nebulizer). Your doctor will teach you the right way to use.
- Do not use if the solution is cloudy, leaking, or has particles.
- If you are also using dornase alfa, do not mix this drug in the same nebulizer as the dornase alfa. If you are taking more than 1 inhaled drug, talk to your doctor about the best order for taking your drugs.
- Follow how to clean carefully.
Capsules for breathing in:
- Do not swallow capsule. The contents of the capsule will be breathed into the lungs.
- Take the capsule out of the foil right before use.
- If any powder stays in the capsule, breathe out fully and repeat. When the capsule is empty, throw it away.
- If using more than 1 type of puffer (inhaler), ask the doctor which puffer to use first.
- Have your puffer (inhaler) use checked with your doctor at each visit. Read and follow facts on how to use the puffer. Make sure you use the puffer the right way.
- Use new puffer (inhaler) with each refill.
- It is given as a shot into a muscle or vein.
- Take a missed dose as soon as you think about it.
- If it is less than 6 hours until the next dose, skip the missed dose and go back to the normal time.
- Do not take 2 doses at the same time or extra doses.
- Call the doctor to find out what to do.
Liquid for breathing in:
- Store in a refrigerator or at room temperature. If stored at room temperature, throw away any part not used after 28 days.
- Do not freeze.
- Protect from light.
Capsules for breathing in:
- Store in the original container at room temperature.
- Store in a dry place. Do not store in a bathroom.
- This drug will be given to you in a hospital or doctor’s office. You will not store it at home.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Tobramycin (Systemic, Oral Inhalation)©2015 Memorial Sloan Kettering Cancer Center - Generated on September 3, 2015