Travelers' Diarrhea and Cholera Vaccine

Adult Medication

Brand Names: Canada


What is this drug used for?

  • It is used to prevent travelers’ diarrhea and cholera.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to travelers’ diarrhea and cholera vaccine or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have a stomach illness like loose stools (diarrhea) or throwing up.
  • If you have an infection or an illness with a fever.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • This drug may not protect all people who use it. You must still do steps to keep from getting these health problems. These may be things like using care when picking food or water and using good cleanliness. Talk with the doctor.
  • If you are on a low-salt or salt-free diet, talk with your doctor.
  • If you are also taking the oral typhoid vaccine, do not take it within 8 hours of this drug.
  • Do not give to a child younger than 2 years of age.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Belly pain.
  • Upset stomach or throwing up.
  • Loose stools (diarrhea).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
  • Take by mouth only.
  • Take on an empty stomach. Do not eat, drink, or take other drugs by mouth for 1 hour before and for 1 hour after taking this drug.
  • This drug must be mixed with a certain liquid (buffer solution) before it is taken. To make the buffer solution, open the buffer packet and melt the granules in 5 ounces (150 mL) of cool water. Do not mix with any other liquid.
  • Shake vaccine liquid and add to the mixture. Mix well and drink.
  • Drink within 2 hours of mixing.
  • Take the last dose at least 1 week before you travel to the high risk place.

What do I do if I miss a dose?

  • If you miss the second dose and it has been less than 6 weeks since your last dose, take the missed dose as soon as you think about it.
  • Do not take 2 doses at the same time or extra doses.
  • If you are not sure what to do if you miss a dose, call your doctor.

How do I store and/or throw out this drug?

  • Before mixing, store in the refrigerator.
  • Do not freeze.
  • Before mixing, this drug may be stored at room temperature for up to 2 weeks. This can be done 1 time only.
  • After mixing, you may store at room temperature for 2 hours.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

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