This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
Reclast; Zometa [DSC]
Aclasta; PMS-Zoledronic Acid [DSC]; TARO-Zoledronic Acid; Zoledronic Acid - Z; Zometa
- It is used to treat soft, brittle bones (osteoporosis).
- This drug is not approved for use in children. However, the doctor may decide the benefits of taking this drug outweigh the risks. If your child has been given this drug, ask the doctor for information about the benefits and risks. Talk with the doctor if you have questions about giving this drug to your child.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child has low calcium levels.
- If your child has kidney disease.
- If your child is taking another drug that has the same drug in it.
- If your child is using another drug like this one.
If your child is pregnant or breast-feeding a baby:
- Do not give this drug to your child if she is pregnant.
- Be sure your child does not breast-feed a baby while taking this drug. Your child may also need to avoid breast-feeding a baby for some time after her last dose. Talk with your child’s doctor to see if your child needs to avoid breast-feeding a baby after her last dose.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take this drug with all of his/her drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- Worsening of asthma has happened in people taking drugs like this one. Talk with the doctor.
- This drug may raise the chance of a broken leg. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have your child get a bone density test as you have been told by your child’s doctor.
- This drug works best when used with calcium/vitamin D and weight-bearing workouts like walking or PT (physical therapy).
- Give calcium and vitamin D as you were told by your child’s doctor.
- Follow the diet and workout plan that your doctor told you about.
- This drug may cause jawbone problems. The risk may be higher the longer your child takes this drug. The risk may be higher if your child has cancer, dental problems, dentures that do not fit well, anemia, blood clotting problems, or an infection. The risk may also be higher if your child is having dental work, gets chemo or radiation, or takes other drugs that may cause jawbone problems (like some steroid drugs). Talk with your child’s doctor if any of these apply to your child, if your child will be having dental work, or if your child takes other drugs that may cause jawbone problems. There are many drugs that can do this. Ask your child’s doctor or pharmacist if you are not sure. Call your child’s doctor right away if your child has jaw swelling or pain.
- Have your child get a dental exam before starting this drug.
- Take care of your child’s teeth. See a dentist often.
- You will need to be sure that your child is not dehydrated before getting this drug. Check with the doctor to see if you need to have your child drink extra fluids before getting this drug.
- If your child is of childbearing age, your child’s doctor may have your child take a pregnancy test before starting this drug to show that she is NOT pregnant.
- This drug may cause fertility problems. This may affect being able to have children. Talk with the doctor.
If your child is or may be sexually active:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy.
- Have your child use birth control while taking this drug and for some time after the last dose. Ask the doctor how long your child must use birth control. If your child becomes pregnant, call the doctor right away.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
- Very bad bone, joint, or muscle pain.
- Any new or strange groin, hip, or thigh pain.
- Feeling agitated.
- Shortness of breath.
- A burning, numbness, or tingling feeling that is not normal.
- Low mood (depression).
- Chest pain.
- Change in eyesight, eye pain, or very bad eye irritation.
- Mouth sores.
- Trouble swallowing.
- Very bad pain when swallowing.
- Fever, chills, or sore throat; any unexplained bruising or bleeding; or feeling very tired or weak.
- Very bad headache.
- Swelling in the arms or legs.
- Vaginal itching or discharge.
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:
- Feeling dizzy, tired, or weak.
- Upset stomach or throwing up.
- Belly pain or heartburn.
- Diarrhea or constipation.
- Flu-like signs.
- Back, bone, joint, muscle, or neck pain.
- Pain in arms or legs.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.
Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
- Have your child drink at least 2 glasses of liquids a few hours before getting this drug.
- Have your child drink lots of noncaffeine liquids unless told to drink less liquid by your child’s doctor.
- Acetaminophen may be given to lower fever and chills.
- Call your child’s doctor to find out what to do.
- If you need to store this drug at home, talk with your child’s doctor, nurse, or pharmacist about how to store it.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
© 2019 Wolters Kluwer Clinical Drug Information, Inc. and its affiliates and/or licensors. All rights reserved.