Twenty Year Anniversary of BRCA1

Pictured: Mark Robson, Noah Kauff, Zsofia Stadler & Kenneth Offit (Left to right) Medical oncologist Mark Robson, gynecologist Noah Kauff, medical oncologist Zsofia Stadler, and Clinical Genetics Service Chief Kenneth Offit are applying genetic insights to improve the care of cancer patients.

The recent film “Decoding Annie Parker” chronicles the discovery of BRCA1, an inherited gene mutation associated with an increased risk of breast and ovarian cancers. Together with uncovering BRCA2, the breakthrough transformed the way doctors aim to prevent and treat hereditary cancers.

Since BRCA1’s discovery, in 1994, Memorial Sloan Kettering specialists have continued to make significant strides in hereditary genetics. Learn more about the last 20 years’ progress and our current hereditary genetics research.

20 Years of Progress in Understanding Hereditary Breast Cancer20 Years of Progress in Understanding Hereditary Breast Cancer

More on BRCA1 & BRCA2

Pictured: Kenneth Offit
Twenty Years after BRCA Discovery, Progress in Prevention and Early Detection
Memorial Sloan Kettering Clinical Genetics Service Chief Kenneth Offit discusses ways for women to clearly assess their risk for breast and ovarian cancers.
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Pictured: Kenneth Offit, Alexandra Heerdt, Emily Glogowski & Max Gomez
Genetic Counseling, Testing, and Treatment for People with BRCA Gene Mutations
Cancer genetics experts say the discovery of the <em>BRCA</em> gene mutations has transformed the way doctors prevent and treat hereditary cancers. Read the post and watch the video.
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Pictured: Noah Kauff
Inherited Gene Mutations Linked to Rare Form of Uterine Cancer
A study has found that mutations in the gene <em>BRCA1</em> are associated with an increased likelihood of developing a rare, aggressive form of uterine cancer.
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Pictured: Megan Harlan Fleischut & Kenneth Offit
Genetic Counseling and Genetic Screening for Cancer
Genetic counselor Megan Harlan Fleischut discusses hereditary cancers and the services offered by Memorial Sloan Kettering’s clinical genetics experts.
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Charles Sawyers, Kenneth Offit, and Larry Norton
Three Memorial-Sloan Kettering Researchers Receive Special Awards by the American Society of Clinical Oncology
Charles Sawyers, Larry Norton, and Kenneth Offit are being honored with special awards at the annual meeting of the world’s leading professional organization for cancer physicians and researchers.
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In this video, genetic counselor Sherry Boyer explains why some women have a higher risk of developing breast cancer.

More on Hereditary Cancer Genetics

Pictured: Mark Robson
Too Much Information? Geneticist Mark Robson Discusses Accidental Genetic Findings
As genome sequencing of tumors becomes more routine, it increases the odds that additional disease-related mutations may be discovered by accident, a development that raises profound issues.
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Pictured: Megan Harlan Fleischut & Kenneth Offit
Hereditary Cancer & Genetics
If you have a family history of cancer, the Clinical Genetics Service at Memorial Sloan Kettering can help you to understand your risk for disease.
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Pictured: Douglas Levine
Aggressive Ovarian Cancer May Be Caused by a Single Gene Mutation
Researchers have identified a genetic mutation that appears to cause a rare but very aggressive type of ovarian cancer in young women.
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In this video, Dr. Max Gomez leads a panel discussion on genetic counseling and cancer care for people with hereditary forms of cancer.