Clinical Updates & Insights

Our recent research confirms that total gastrectomy should be considered for all patients with the CDH1 gene mutation that carries a high risk for developing hereditary diffuse gastric cancer.

There is no established standard therapy for the treatment of mantle cell lymphoma (MCL). Instead, there is a range of treatment options and, to date, there has been a dearth of data to assist in clinical decision-making.

Recent research from Memorial Sloan Kettering shows that dual-energy contrast-enhanced digital mammography (CEDM) is as sensitive in detecting breast cancer as contrast-enhanced breast MRI when both were compared with standard mammograms.

Our research shows that most women diagnosed with either breast or gynecologic cancer have concerns about how treatment may affect their sexual and vaginal health. Moreover, they want their healthcare providers to initiate the discussion.

Advances in our understanding of the biology of breast cancer are guiding the development of individualized treatment plans. We outline the clinical case history of young breast cancer patient, Elizabeth Shelley, including our rational for not proceeding with the originally prescribed chemotherapy.

Performing minimally invasive robotic cystectomy and bladder reconstruction in one operation provides a viable alternative to open surgery with less blood loss, decreased pain, diminished wound morbidity, and the potential for faster return of bowel function.

Recent data from Memorial Sloan Kettering shows that a real-time breast ultrasound exam after second opinion review of outside, static breast ultrasound images led to a change in the initially prescribed management in 32.5 percent of included patients.

Active surveillance of prostate cancer is being increasingly utilized for men with low-risk cancer. But some men with potentially life-threatening cancers are being inadvertently enrolled in such programs, driving the need for more accurate decision-making tools such as the 4Kscore test developed at Memorial Sloan Kettering.

Hepatic arterial infusion chemotherapy given to colorectal cancer patients with liver metastases extends their survival by almost two years, according to a large retrospective study from Memorial Sloan Kettering recently published in the JCO.

American Thyroid Association guidelines endorse close observation as a treatment option for many small papillary thyroid tumors rather than surgery. MSK endocrinologist Michael Tuttle MD discusses why monitoring such cancers is a viable approach.