Clinical Updates & Insights

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Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

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222 Clinical Updates found

Clinical Update

Everolimus Plus Bevacizumab Effective for First-Line Treatment of Advanced Papillary Variant Renal Cell Carcinoma

Everolimus plus bevacizumab demonstrates robust activity in treatment-naïve patients with advanced papillary variant nonclear cell renal cell carcinoma.

  • Monday, November 9, 2020

Clinical Update

Total Gastrectomy Indicated for Patients with Stomach Cancer Gene Mutations Regardless of Family History

Total gastrectomy is indicated for patients with stomach cancer gene mutations regardless of family history.

  • Monday, November 9, 2020

Clinical Update

Case Study Illustrates Need for More Effective Treatment Options for Aggressive Pituitary Adenomas

Pituitary adenomas continue to grow in a small subset of patients despite treatment with standard surgery and radiotherapy. Recognizing the significant unmet needs in this cohort, we recently published a review of the latest treatment options.

  • Wednesday, October 14, 2020

Clinical Update

Review: Benefits and Future Directions for Proton Therapy in Head and Neck Cancer

Our review summarizes recent developments in treatment planning and delivery, existing clinical evidence, and ongoing prospective trials in major head and neck cancers that may further increase the therapeutic window of proton therapy for patients with head and neck cancer.

  • Tuesday, October 13, 2020

Clinical Update

Select Kidney Cancer Patients with Chronic Kidney Disease Can Avoid Dialysis After Surgery

Results from our recent retrospective study show that surgically managed patients with kidney cancer and comorbid mild to moderate chronic kidney disease (CKD) experience significantly less need for future dialysis.

  • Monday, October 12, 2020

Clinical Update

Neoadjuvant Chemotherapy May Affect Young Women’s Decisions to Pursue Fertility Preservation Counseling

Young women with breast cancer who receive neoadjuvant chemotherapy are more likely to decline referral to reproductive endocrinology and infertility specialists than women who receive adjuvant chemotherapy.

  • Tuesday, September 8, 2020

Clinical Update

Persistent Radiation-Induced Alopecia Has Distinctive Features and May Benefit from Treatment

Persistent radiation-induced alopecia in patients with primary central nervous system tumors or head and neck sarcomas is dose-dependent and has distinctive clinical and trichoscopic features, but can benefit from treatment.

  • Tuesday, September 8, 2020

Clinical Update

Select Patients with Thyroid Cancer May Not Require Prophylactic Central Compartment Neck Dissection

Select patients with papillary thyroid carcinoma with clinically involved lateral neck nodes may not require prophylactic central compartment neck dissection, enhancing quality of life.

  • Monday, August 17, 2020

Clinical Update

A Single Surviving Myeloma Cell Can Seed Accelerated Relapse

A single surviving myeloma cell can seed accelerated relapse, and more than 20 percent of nonsynonymous mutations at relapse may be induced by exposure to chemotherapy such as platinum and high-dose melphalan after autologous stem cell transplant.

  • Friday, August 14, 2020

Clinical Update

Review: Our Experience with Convection Enhanced Delivery for Diffuse Intrinsic Pontine Glioma

Convection enhanced delivery, an innovative technique that directly infuses a therapeutic agent into a brain tumor through a cannula, bypassing the blood-brain barrier, is safe and feasible for treating diffuse intrinsic pontine glioma in children.

  • Friday, August 14, 2020