Etonogestrel

Pediatric Medication
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This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

Brand Names: US

Nexplanon

Brand Names: Canada

Nexplanon

What is this drug used for?

  • It is used to prevent pregnancy.

What do I need to tell the doctor BEFORE my child takes this drug?

  • If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
  • If your child has any of these health problems: Liver disease, liver tumors, or unexplained vaginal bleeding.
  • If your child has ever had any of these health problems: Blood clots, breast cancer or other kind of cancer where hormones make it grow, heart attack, or stroke.
  • If your child has given birth within the last 21 days.
  • If your child has not started having menstrual periods.
  • If your child is pregnant or may be pregnant. Do not give this drug to your child during pregnancy.

This is not a list of all drugs or health problems that interact with this drug.

Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

  • Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
  • Be sure your child has regular breast exams and gynecology check-ups. Your child will also need to do breast self-exams as the doctor has told you.
  • After this drug has been put in, your child may need to use a non-hormone birth control like condoms for some time. Talk with the doctor.
  • If your child cannot feel the implant or thinks that the implant has broken or bent inside the arm, talk with the doctor.
  • Problems have happened when this drug was put in or taken out. These include pain; burning, numbness, or tingling; dizziness; passing out; bruising or bleeding; scars; or infection. If you have questions, talk with the doctor.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • If your child drinks grapefruit juice or eats grapefruit often, talk with your child’s doctor.
  • If your child gets pregnant while taking this drug, the chance of pregnancy outside of the uterus (ectopic pregnancy) may be raised.
  • Blood clots have happened with this drug. Sometimes, these blood clots have been deadly. Talk with the doctor.
  • Talk with the doctor if your child will need to be still for long periods of time like long trips, bedrest after surgery, or illness. Not moving for long periods may raise the chance of blood clots.
  • A cyst on the ovary may rarely happen.
  • If your child has high blood sugar (diabetes), talk with the doctor. This drug can raise blood sugar.
  • Check your child’s blood sugar as you have been told by the doctor.
  • High blood pressure has happened with this drug. Have your child’s blood pressure checked as you have been told by the doctor.
  • This drug may affect certain lab tests. Tell all of your child’s health care providers and lab workers that your child takes this drug.
  • Certain drugs, herbal products, or health problems may cause hormone-based birth control to not work as well. Be sure the doctor knows about all of your child’s drugs and health problems. You will need to see if your child also needs to use a non-hormone form of birth control like condoms.
  • The chance of getting cervical cancer may be higher in people who take hormone-based birth control. However, this may be due to other reasons. If you have questions, talk with the doctor.
  • Some studies have shown the risk of breast cancer is raised when taking hormone-based birth control for a long time. However, other studies have not shown this risk. If you have questions, talk with the doctor.
  • This drug does not stop the spread of diseases like HIV or hepatitis that are passed through having sex. Be sure your child does not have any kind of sex without using a latex or polyurethane condom.
  • If this drug is removed and your child does not want to get pregnant, have her use birth control right after it is removed. Pregnancy has happened shortly after this drug was removed.
  • A pregnancy test will be done to show that your child is NOT pregnant before starting this drug. If your child gets pregnant while taking this drug, call the doctor right away.
  • Tell the doctor if your child is breast-feeding a baby. You will need to talk about any risks to the baby.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of liver problems like dark urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Signs of gallbladder problems like pain in the upper right belly area, right shoulder area, or between the shoulder blades; yellow skin or eyes; fever with chills; bloating; or very upset stomach or throwing up.
  • Signs of skin infection like oozing, heat, swelling, redness, or pain.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • Depression or other mood changes.
  • Eyesight changes or loss, bulging eyes, or change in how contact lenses feel.
  • A lump in the breast, breast pain or soreness, or nipple discharge.
  • Flu-like signs.
  • Vaginal bleeding that is not normal.
  • This drug may cause your child to swell or keep fluid in the body. Tell your child’s doctor if swelling, weight gain, or trouble breathing happens after this drug is given.
  • Call the doctor right away if your child has signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

  • Weight gain.
  • Dizziness or headache.
  • Pimples (acne).
  • Vaginal irritation.
  • Period (menstrual) changes. These include spotting between cycles or very light periods.
  • Irritation where rod was placed.
  • Stomach pain.
  • Throat irritation.
  • Back pain.
  • Upset stomach.
  • Feeling nervous and excitable.

These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.

You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

  • A rod is placed under the skin in the upper arm. This is a minor surgery. The rod must be changed every 3 years.

What do I do if my child misses a dose?

  • Call your child’s doctor to find out what to do.

How do I store and/or throw out this drug?

  • If you need to store this drug at home, talk with your child’s doctor, nurse, or pharmacist about how to store it.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last Reviewed Date

2023-11-07

Copyright

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Last Updated

Monday, December 12, 2022