The Luis Parada Lab

The Parada lab uses genetically engineered mouse models to recapitulate and study human disease. These mouse strains are used to understand the natural history of tumors of the nervous system, including glioblastoma multiforme (GBM), malignant peripheral nerve sheath tumors (MPNST), neurofibromas, and other diseases associated with neurofibromatosis (NF1). We seek to develop mouse cancer models based on concrete hypotheses and to rapidly transfer findings for validation in human cancer samples.

Luis Parada

Luis F. Parada, PhD

Director, Brain Tumor Center; Albert C. Foster Chair; American Cancer Society Research Professor


Research Focus

Developmental biologist Luis F. Parada uses genetically engineered mouse models to study neurofibromatosis, brain tumors, cancer stem cells, and tumor progression.


PhD, Massachusetts Institute of Technology

Lab Members

  • Cell lineage-based stratification for glioblastoma. Wang Z, Sun D, Chen Y-J, Xie XP, Shi Y, Tabar V, Brennan CW, Bale TA,  Jayewickrem, CD, Laks DR, Alcantara Llaguno S, and Parada LF., 2020, Cancer Cell, in Press.
  • High resolution subventricular zone stem cell niche transcriptome reveals features of lineage, anatomy, and aging.  Xie XP, Laks DR,  Sun D, Poran A,  Laughney AM,  Wang Z, Sam J, Belenguer G, Fariñas I, Elemento O, Zhou X, Parada LF., 2020, Submitted.
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Selected Achievements
  • Member, National Academy of Science (2011)
  • Fellow of American Association for the Advancement of Science (2009)
  • Member, National Academy of Medicine- Former Institute of Medicine (2007)
  • The Academy of Medicine, Engineering and Sciences of Texas (TAMEST) (2007)
  • Member, American Academy of Arts and Sciences (2007)
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  • Member, Dana Alliance for Brain Initiatives (2003)
  • Professor, American Cancer Society Research (2002)