Histiocytosis is a general name for a group of diseases that cause higher than normal levels of immune cells called histiocytes. Langerhans cell histiocytosis (LCH) is a rare blood cancer and is the most common form of histiocytosis in children. It forms when white blood cells called Langerhans cells become abnormal and grow in different parts of the body. LCH is most common in children under age 10 but can occur at any age. MSK investigators do a lot of research related to histiocytosis. MSK Kids is a major referral center for people with this disease.
At MSK Kids, our program for children with histiocytosis features:
- a monthly tumor board where doctors come together to discuss patients’ cases
- advanced genetic testing to identify the molecules driving the growth of the disease
- treatment with targeted therapies
- participation in the North American Consortium for Histiocytosis clinical trials group, offering patients access to investigational treatments.