Other Types of Sarcoma

In general, sarcomas that are not classified as osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, or desmoplastic small round cell tumors are rare in children, adolescents, and young adults.

Treatment for these soft tissue sarcomas is tailored to each patient, and can include a combination of chemotherapy, surgery, and radiation therapy.

These tumors are classified by the tissue in which they originate, including:

Fibrohistiocytic Tumors

  • Malignant fibrous histiocytoma (MFH), also called spindle cell sarcomas

Tumors of Adipose Tissue

  • Liposarcoma

Tumors of Bone and Cartilage

  • Extraosseous osteosarcoma
  • Extraosseous myxoid chondrosarcoma
  • Mesenchymal chondrosarcoma

Tumors of Fibrous Tissue

  • Fibromatoses (desmoid tumors)
  • Fibrosarcoma
  • Dermatofibrosarcoma
  • Low-grade fibromyxoid sarcoma

Tumors of the Gastrointestinal Tract

  • Gastrointestinal stromal tumors (GIST)

Tumors of More Than One Tissue Type

  • Malignant mesenchymoma
  • Malignant triton tumor
  • Malignant ectomesenchymoma

Tumors of the Peripheral Nervous System

  • Malignant schwannoma (malignant peripheral nerve sheath tumor)

Tumors of Smooth Muscle

  • Leiomyosarcoma

Tumors of Unknown Origin

  • Alveolar soft part sarcoma (ASPS)
  • Clear cell sarcoma (malignant melanoma of soft parts)
  • Epithelioid sarcoma
  • Synovial sarcoma
  • Undifferentiated soft tissue sarcoma

Tumors of Vascular Structures

  • Angiosarcoma
  • Hemangioendothelioma
  • Hemangiopericytoma
  • Lymphangiosarcoma