What is it?
Lab studies of magnolia bark extract suggest anti-inflammatory and anticancer properties, but studies in humans are needed.
Magnolia officinalis is a flowering herb that has been used in traditional Chinese medicine to treat anxiety, depression, stress, nervousness, and sleep-related problems. It is also used to regulate gastrointestinal motility and is found in herbal formulas such as Ma Zi Ren Wan. Lab studies suggest that some compounds from magnolia bark extract may have anticancer properties, but this has not been studied in cancer patients.
Data in humans are limited. Small studies in humans suggest magnolia may help relieve menopausal symptoms, manage weight, and maintain oral health. However, these studies used magnolia in combination with other compounds.
What are the potential uses and benefits?
- To prevent cancer
Lab studies suggest magnolia bark extract has anticancer properties, but clinical trials are needed to confirm these effects. - To treat diabetes
Magnolia bark extract and its active compounds lowered blood sugar in the lab, but human studies are needed. - To prevent inflammation
Animal studies have shown that magnolia bark extract reduces pain and inflammation. - As an antibacterial agent
Lab studies suggest magnolia bark extract may reduce the bacterium that causes acne and some types of infections. - To reduce anxiety
Lab studies show that magnolia has anxiolytic effects. Human data are lacking. - To reduce depression
Lab studies show that magnolia has antidepressant effects. Human studies are needed.
What are the side effects?
- Skin rash has been reported with the use of cosmetics containing magnolia bark extract.
What else do I need to know?
Do Not Take if:
- You are taking diabetes medications: Magnolia bark extract may enhance their effects. Clinical relevance is not known.
- You are taking sleep or anxiety medications: Magnolia bark extract may increase their effects. Clinical relevance is not known.
- You are taking blood thinners: Magnolia bark extract may increase bleeding risk. Clinical relevance is not known.
- You are taking CYP450 substrate drugs: Magnolia bark extract may alter the effects of these drugs. Clinical relevance is not known.
- You are taking P-gp substrate drugs: Magnolia bark extract may alter the effects of these drugs. Clinical relevance is not known.
- You are taking UGT substrate drugs: Magnolia bark extract may alter the effects of these drugs. Clinical relevance is not known.