Colesevelam

This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

Brand Names: US

Welchol

Brand Names: Canada

APO-Colesevelam; Lodalis

What is this drug used for?

  • It is used to lower cholesterol.
  • If your child has been given this drug for some other reason, talk with the doctor about the benefits and risks. Talk with the doctor if you have questions or concerns about giving this drug to your child.

What do I need to tell the doctor BEFORE my child takes this drug?

  • If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
  • If your child has high triglycerides or has ever had pancreatitis caused by high triglycerides.
  • If your child has ever had a bowel block.
  • If your child has a slow moving GI (gastrointestinal) tract or has had stomach or bowel surgery.

This is not a list of all drugs or health problems that interact with this drug.

Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

  • Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
  • High triglyceride levels have happened with this drug. Tell your child’s doctor if your child has ever had high triglyceride levels.
  • Have your child’s blood work checked often. Talk with your child’s doctor.
  • If your child has high blood sugar (diabetes), you will need to watch your child’s blood sugar closely.
  • If your child takes vitamins by mouth, give the vitamins at least 4 hours before your child takes this drug.
  • If your child takes other drugs, they may need to be given at a different time than this drug. Check with the doctor or pharmacist about the best time to give them.
  • If your child has phenylketonuria (PKU), talk with your child’s doctor. Some products have phenylalanine.

If your child is or may be sexually active:

  • Birth control pills may not work as well to prevent pregnancy if taken at the same time as this drug. If your child is taking a birth control pill, have her take it at least 4 hours before taking this drug.

If your child is pregnant or breast-feeding a baby:

  • Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks to your child and the baby.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
  • Trouble swallowing.
  • Severe constipation or stomach pain. These may be signs of a severe bowel problem.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

  • Constipation.
  • Heartburn.
  • Headache.
  • Nose or throat irritation.

These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.

You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

All products:

  • Give this drug with meals.
  • Have your child follow the diet and workout plan your child’s doctor told you about.
  • Have your child drink lots of noncaffeine liquids every day unless told to drink less liquid by your child’s doctor.

Powder for suspension:

  • Mix with 1 cup (8 ounces/240 mL) of water, fruit juice, or diet soda. Stir well and have your child drink.
  • Do not give the powder dry.

Tablets:

  • Give this drug by mouth with water or other liquid.
  • If your child has trouble swallowing, talk with the doctor.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it, with a meal.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses at the same time or extra doses.

How do I store and/or throw out this drug?

  • Store at room temperature in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last Reviewed Date

2022-07-19

Copyright

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Last Updated

Monday, December 12, 2022