Rotigotine

This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

Brand Names: US

Neupro

Brand Names: Canada

Neupro

What is this drug used for?

  • It is used to treat Parkinson’s disease.
  • It is used to treat restless leg syndrome.

What do I need to tell my doctor BEFORE I take this drug?

  • If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

This drug may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

For all uses of this drug:

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
  • Check blood pressure and heart rate as the doctor has told you.
  • If you are allergic to sulfites, talk with your doctor. Some products have sulfites.
  • The patch may have metal. Take off the patch before an MRI or cardioversion.
  • Do not stop this drug without talking to your doctor. When you stop this drug, you may have signs of withdrawal. If you need to stop this drug, follow how to stop it as your doctor has told you. Call your doctor right away if you have any of these signs when lowering the dose or stopping this drug: fever, confusion, severe muscle stiffness, not caring about things, anxiety, depression, feeling tired, trouble sleeping, sweating, or pain.
  • Talk with your doctor before you use alcohol, marijuana or other forms of cannabis, or prescription or OTC drugs that may slow your actions.
  • Avoid use of heat sources (such as sunlamps, tanning beds, heating pads, electric blankets, heat lamps, saunas, hot tubs, heated waterbeds). Avoid long, hot baths or sunbathing. Your temperature may rise and cause too much drug to pass into your body.
  • If you get a skin rash or irritation from the patch, avoid sunlight on the area until the skin heals. Sun may cause the irritated skin to change color.
  • Neuroleptic malignant syndrome (NMS) is a severe and sometimes deadly health problem that has happened when drugs like this one were stopped all of a sudden. NMS has also happened when the dose was lowered. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, severe headache, confusion, change in thinking, fast or abnormal heartbeat, or are sweating a lot.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

Restless leg syndrome:

  • Tell your doctor if your signs become worse or start earlier in the day.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Strong urges that are hard to control (such as eating, gambling, sex, or spending money).
  • Chest pain or pressure.
  • Fast or abnormal heartbeat.
  • Mental, mood, or behavior changes that are new or worse.
  • Hallucinations (seeing or hearing things that are not there).
  • Feeling confused.
  • Fever.
  • Muscle pain.
  • Muscle stiffness.
  • Trouble controlling body movements that is new or worse.
  • Change in eyesight.
  • Change in sex interest.
  • This drug may cause you to swell or keep fluid in your body. Tell your doctor if you have swelling, weight gain, or trouble breathing.
  • Some people have fallen asleep during activities like driving, eating, or talking. Some people did not feel sleepy and felt alert right before falling asleep. This has happened up to 1 year after this drug was started. If you fall asleep during activities, do not drive or do other tasks or actions that call for you to be alert while you take this drug. Call your doctor right away if this happens or you feel very sleepy.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Constipation, diarrhea, throwing up, or upset stomach.
  • Decreased appetite.
  • Feeling dizzy, sleepy, tired, or weak.
  • Strange or odd dreams.
  • Headache.
  • Sweating a lot.
  • Trouble sleeping.
  • Joint pain.
  • Irritation where this drug was used.
  • Dry mouth.
  • Nose or throat irritation.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to your national health agency.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Do not use patches that are cut or do not look right.
  • Wash your hands before and after use.
  • Put patch on clean, dry, healthy skin on the belly, hip, side, shoulder, upper leg, or upper arm.
  • Put patch on at the same time of day.
  • Do not put on skin that is irritated or damaged. Do not put on an area with skin folds or skin that will be rubbed by tight clothes.
  • Do not put on skin where you have just used creams, oils, lotions, powder, or other skin products. The patch may not stick as well.
  • Shave hair at a site 3 days before putting a patch on it.
  • Press patch firmly in place for 30 seconds when putting it on.
  • Move the patch site with each new patch. Do not put on the same site for 14 days.
  • Be careful to not knock loose the patch while bathing or showering.
  • If the patch falls off, put a new one on.
  • If the patch loosens, put tape ONLY on the edges of the patch to hold it in place.
  • When patch is taken off, wash site with soap and water.
  • Keep using this drug as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

  • Put on a missed patch as soon as you think about it after taking off the old one.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not put on more than 1 patch at a time.

How do I store and/or throw out this drug?

  • Store at room temperature in a dry place. Do not store in a bathroom.
  • Store patches in pouch until ready for use.
  • After you take off a skin patch, be sure to fold the sticky sides of the patch to each other. Throw away used patches where children and pets cannot get to them.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last Reviewed Date

2021-08-03

Copyright

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Last Updated

Monday, December 12, 2022