Gene Editing & Screening

Overview

Ralph Garippa
Director

The Gene Editing & Screening Core Facility (GES Core) brings together complementary technologies aimed at interrogating cancer biology and identifying molecular vulnerabilities of cancer cells.  The GES Core expertly enables all aspects of state-of-the-art technologies in RNA interference and CRISPR-Cas9 mediated gene editing for functional genomics initiatives.

In parallel, towards the identification of chemical probes which influence cancer phenotypes, the GES Core maintains and operates a workstation-based small molecule high throughput screening (HTS) facility using space- and cost-efficient approaches and a multi-pronged, targeted chemical library (I) for chemogenomic studies, (II) to phenocopy new molecular targets with pharmacological agents and (III) to enable bona fide chemical probe and early drug discovery in oncology. Moreover, considering that the microscopy has provided the morphological underpinning to the study of cancer biology, therefore the GES Core offers state-of-the-art automated arrayed 2D/3D laser line confocal imaging using high content screening & and analysis (HCS/HCA) tools.

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GES

People

Members

Jesse Barnes, Ph.D

Research Assistant

Ana Crawford

Lead Assistant

Clare Lewis

Senior Research Assistant

Anniefer Magpusao

Research Assistant

Sanjoy Mehta
Sanjoy Mehta

Senior Research Assistant

Hannah Simandl

Senior Research Technician

Jianmin Yang

Core Facility Manager

Alumni
Myles Fennell
Myles Fennell

Senior Research Scientist

Qing Xiang
Qing Xiang

Research Assistant Specialist

Toshimitsu Takagi
Toshimitsu Takagi

Senior Research Scientist

Alexia Hwang
Alexia Hwang

Research Technician

Justin Ferraro
Justin Ferraro

Research Technician

Trinasia Kelly
Trinasia Kelly

Administrative Assistant

Chandani Limbad
Chandani Limbad

Senior Research Scientist

Hsiu-Yu Liu, MS
Hsiu-Yu Liu

Research Assistant

Sade McCray
Sade McCray

Administrative Assistant II

Antonio Ortiz
Antonio Ortiz

Senior Research Scientist

Marco Vincenzo Russo
Marco Vincenzo Russo

Scientific Manager

Ayana Suber
Daniel Zakheim
Daniel Zakheim

Senior Research Assistant

Yana Zorina
Yana Zorina

Senior Research Scientist

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