Recent MSK Discoveries & Advances

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Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our blog, On Cancer.

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444 News Items found

In the Lab

How Small Chromosomes Compete with Big Ones for a Cell’s Attention

During meiosis, small chromosomes risk being lost in the shuffle. Here’s how they hold their own.

Chromosomes from a human male

Feature

A Changing Melanoma Landscape: How Research Has Improved the Outlook for People with Advanced Disease

Learn about how research led by MSK clinical investigators has transformed the treatment of metastatic melanoma.

Paul Chapman with a patient

In the Lab

New Discovery Explains How the Prostate Gland Regenerates Itself

Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found.

Fluorescent image of mouse prostate gland

Feature

Top Dogs: Meet MSK’s Four-Legged Volunteers

The Caring Canines program at Memorial Sloan Kettering has been going strong for more than 12 years.

Four dogs wearing blue bandanas are held on leashes in a hallway at Memorial Hospital. Three handlers are seen only from the waist down.

In the Lab

Novel Tool Enables Study of Rare Acute Myeloid Leukemia Stem Cells

MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover new findings about acute myeloid leukemia.

An illustration of a samurai riding a horse along a strand of RNA. The samurai’s sword is changing the letter A to the letter I.

In the Lab

Research Uncovers Details about How Gut Microbes Influence the Immune System

Investigators have shown how gut microbes promote the formation of a type of immune cell called regulatory T cells.

Bacteroides bacteria under the microscope

In the Lab

Drug Combination Could Boost the Effectiveness of Immunotherapy against Pancreatic Cancer

Studies conducted in mice reveal a potential way to breach the defenses of pancreatic cancer tumors.

A drawing of a pancreatic tumor represented as a barren landscape, blood vessels as rivers, and immune cells as ships with ammunition.

In the Clinic

Back-to-Back Studies Support the Use of HER2-Targeted Therapies in Multiple Cancers

Results from a clinical trial and animal studies provide support for targeting the HER2 protein in multiple cancer types.

The latest results come from a team of MSK physicians and scientists (from left to right): Bob Li, Hai-Yan Tu, Mackenzie Myers, Flavia Michelini, Emiliano Cocco, Sandra Misale, and Maurizio Scaltriti

In the Clinic

Liquid Biopsy Can Guide Treatment for Women with Metastatic Breast Cancer

By identifying mutations found in a person’s cancer, this blood test can help doctors tailor treatments to those most likely to benefit.

blood tube laying atop DNA sequence

In the Clinic

What’s the Best Way to Screen for Breast Cancer? Abbreviated MRI Beats 3-D Mammography, but Research Is Ongoing

Experts at MSK are exploring more-advanced screening techniques with the goal of detecting breast cancer earlier.

A woman receives a mammogram, and two technicians help her.