Immunology Program

The Jayanta Chaudhuri Lab

Research

Pictured: Jayanta Chaudhuri
Jayanta Chaudhuri, PhD

Laboratory of Molecular and Cellular Immunology

Recombination, genomic integrity, and heterogeneity in B cells
 

scientific diagram

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Publications Highlights

Sharma, R., Smolkin, R. M., Chowdhury, P., Fernandez, K. C., Kim, Y., Cols, M., Alread, W., Yen, W.-F., Hu, W., Wang, Z.-M., Violante, S., Chaligné, R., Li, M. O., Cross, J. R., & Chaudhuri, J. (2023). Distinct metabolic requirements regulate B cell activation and germinal center responses. Nature Immunology, 24(8), 1358–1369. https://doi.org/10.1038/s41590-023-01540-y

Fernandez, K. C., Feeney, L., Smolkin, R. M., Yen, W.-F., Matthews, A. J., Alread, W., Petrini, J. H. J., & Chaudhuri, J. (2022). The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes. eLife, 11, e77073. https://doi.org/10.7554/eLife.77073

Maekawa, K., Yamada, S., Sharma, R., Chaudhuri, J., & Keeney, S. (2022). Triple-helix potential of the mouse genome. Proceedings of the National Academy of Sciences of the United States of America, 119(19), e2203967119. https://doi.org/10.1073/pnas.2203967119

Yewdell, W. T., Smolkin, R. M., Belcheva, K. T., Mendoza, A., Michaels, A. J., Cols, M., Angeletti, D., Yewdell, J. W., & Chaudhuri, J. (2021). Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection. Cell Reports, 37(6), 109961. https://doi.org/10.1016/j.celrep.2021.109961

Mendoza, A., Yewdell, W. T., Hoyos, B., Schizas, M., Bou-Puerto, R., Michaels, A. J., Brown, C. C., Chaudhuri, J., & Rudensky, A. Y. (2021). Assembly of a spatial circuit of T-bet-expressing T and B lymphocytes is required for antiviral humoral immunity. Science Immunology, 6(60), eabi4710. https://doi.org/10.1126/sciimmunol.abi4710

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People

Pictured: Jayanta Chaudhuri

Jayanta Chaudhuri, PhD

  • Immunologist Jayanta Chaudhuri studies the mechanisms of immunoglobulin gene diversification.
  • PhD, Albert Einstein College of Medicine
[email protected]
Email Address
646-888-2357
Office Phone

Members

Jayanta Chaudhuri, PhD
Jayanta Chaudhuri

Principal Investigator

Stephanie Downs-Canner
Stephanie Downs-Canner

Assistant Attending Surgeon

Memorial Sloan Kettering Medical Oncologist Jennifer Lue
Jennifer Lue

Assistant Attending

Francesca Manara
Francesca Manara

Postdoctoral Research Fellow

Keith Fernandez
Keith Fernandez

Graduate Student

Ryan Smolkin
Ryan Smolkin

Graduate Student

Youngjun Kim
Youngjun Kim

Graduate Student

Kalina Belcheva
Kalina Belcheva

Graduate Student

Marisa Lazarus
Marisa Lazarus

Research Technician

Kanelly Reyes
Kanelly Reyes

Research Technician

Veronica Shields
Veronica Shields

Administrative Assistant

Lab Alumni
Rahul Sharma
Rahul Sharma

Postdoctoral Research Fellow

William Alread
William Alread

Research Technician

Priyanka Chowdhury
Priyanka Chowdhury

Graduate Student

William  Yewdell
William T. Yewdell

Postdoctoral Research Fellow

Silva Baburyan
Silva Baburyan

Research Technician

Zahra Hudda

Pediatric Hematology-Oncology Fellow

Montserrat Cols Vidal
Montserrat Cols Vidal

Lab Manager

Wei-Feng Yen
Wei-Feng Yen

Graduate Student

Joseph N. Pucella
Joseph N. Pucella

Faculty Research Instructor, NYU School of Medicine, New York, NY

Laura Nicolas, PhD
Laura Nicolas

Postdoctoral Research Fellow

William Terry

Pediatric Hematology-Oncology Fellow

Kayleigh-Herrick Reynolds
Kayleigh-Herrick Reynolds

Research Technician

Bharat Vaidyanathan
Bharat Vaidyanathan

Graduate Student

Lauren J. Dimenna
Lauren J. Dimenna

Graduate Student

Simin Zheng
Simin Zheng

Graduate Student

Bao Q. Vuong

Postdoctoral Research Fellow

Allysia Matthews
Allysia Matthews

Graduate Student

Urszula Nowak

Graduate Student

Lab Affiliations

Lab News & Events

Upcoming event

Loop Extrusion and the Assembly of Polymorphonuclear Shapes

Memorial Sloan Kettering Cancer Center
Rockefeller Research Laboratories
430 East 67th Street
RRL-120 (Auditorium)
New York, NY 10065

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Jayanta Chaudhuri discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


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