Structural Biology Program

The Nikola Pavletich Lab

Research

Pictured: Dr. Nikola Pavletich
Nikola P. Pavletich, PhD
Stephen and Barbara Friedman Chair

Our research group is interested in understanding, at the structural and mechanistic levels, the maintenance of genomic integrity and the control of cell growth, both of which figure prominently in cancer. In the area of growth control, our recent work is focused on the mTOR pathway that controls multiple aspects of cell growth and homeostasis. Our work on genomic integrity ranges from the Fanconi Anemia pathway, which responds to DNA interstrand crosslinks, to the ATR and ATM checkpoint kinases that coordinate the cell’s response to replication stress and DNA double-strand breaks, respectively. Common to these genomic integrity pathways is eventual repair by homologous recombination, a process that has been a longstanding focus of our research.

Research Projects

Nikola Pavletich Lab Group

Publications Highlights

People

Pictured: Dr. Nikola Pavletich

Nikola P. Pavletich, PhD

Stephen and Barbara Friedman Chair

  • The Pavletich laboratory studies the structural biology of pathways that control cell growth and maintain the integrity of the genome.
  • PhD, Johns Hopkins University
[email protected]
Email Address
212-639-8544
Office Phone

Members

Yehuda Goldgur
Yehuda Goldgur

Associate Laboratory Member & Head, X-Ray Crystallography Core Facility

Buren Li
Buren Li

Research Technician

Nikola Pavletich, PhD
Nikola Pavletich

Member

Madellyn Sosa
Madellyn Sosa

Administrative Assistant

Renjing Wang
Renjing Wang

Research Fellow

Haijuan Yang
Haijuan Yang

Senior Research Scientist

Marie Benton
Marie Benton
Ankita Dhar
Ankita Dhar

Research Assistant

Christopher Peralta
Christopher Peralta
Christopher Warren
Christopher Warren
Lab Alumni
Buren Li
Buren Li

Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center, New York, NY

Lab Affiliations

Get in Touch

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Nikola P. Pavletich discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


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This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

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