Immunology Program

The Alexander Rudensky Lab

Research

Alexander Rudensky, PhD
Alexander Rudensky, PhD
Chair, Immunology Program, SKI; Director, Ludwig Center at MSK

Our research is focused on understanding the molecular mechanisms governing the differentiation and function of CD4 T lymphocytes and their role in immunity and tolerance. Major areas of interest include: the molecular and cellular mechanisms governing the differentiation and function of regulatory T cells; the roles these cells play in control of autoimmunity, tumor immunity, and immunity to infections, and in the maintenance of immune homeostasis at environmental interfaces. We are particularly interested in understanding the role of the forkhead family transcription factor Foxp3 in establishing and maintaining immune homeostasis; and in the plasticity of regulatory T cell transcriptional and functional programs and the molecular mechanisms of regulatory T cell lineage stability.

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The Alexander Rudensky Lab

Publications Highlights

People

Alexander Rudensky, PhD

Alexander Rudensky, PhD

Chair, Immunology Program, SKI; Director, Ludwig Center at MSK

  • Immunology Program Chair Alexander Rudensky focuses on immunological tolerance and the differentiation and function of T cells.
  • PhD, Gabrichevsky Institute for Microbiology and Epidemiology
[email protected]
Email Address
646-888-3109
Office Phone

Members

George Plitas, MD
George Plitas

Assistant Attending, Breast Service

Emma Andretta
Emma Andretta

Technician

Charlotte Ariyan
Charlotte Ariyan

Associate Attending, Gastric & Mixed Tumor Service

Giogi Beroshvili
Giorgi Beroshvili

Graduate Student

Regina Bou Puerto
Regina Bou Puerto

Graduate Student

Allen Y. Chen

Research Fellow

Spencer Chen, PhD
Spencer Chen

Research Fellow

Beibei (Bella) Fang
Beibei (Bella) Fang

Graduate Student

Joe N. Frost, DPhil
Joe N. Frost

Research Fellow

Aazam Ghelani

Graduate Student

Paolo Giovanelli
Paolo Giovanelli

Graduate Student

Nima Hooshdaran
Nima Hooshdaran

Graduate Student

Beatrice Hoyos
Beatrice Hoyos

Visiting Investigator

Jian Hu

Senior Research Scientist

Xiao Huang, PhD
Xiao Huang

Research Fellow

Ainsley Lockhart, PhD
Ainsley Lockhart

Research Fellow

Cheryl Mai
Cheryl Mai

MD-PhD Student

Anthony Michaels

Graduate Student

Fatima Salman
Fatima Salman

Technician

Lion Uhl, PhD
Lion Uhl

Research Fellow

Aparna Vancheswaran

Research Fellow

Eric Wang
Eric Y. Wang

MD-PhD Student

Lab Alumni
Paula D. Bos, PhD
Paula D. Bos

Postdoctoral Fellow

Georg Gasteiger, MD
Georg Gasteiger

Postdoctoral Fellow

Aaron Arvey, PhD
Aaron Arvey

Postdoctoral Fellow

Yongqiang Feng, PhD
Yongqiang Feng

Research Fellow

Andrew Levine
Andrew Levine

MD/PhD Student

Joris van der Veeken, PhD
Joris van der Veeken

Research Fellow

Clarissa Campbell Menezes
Clarissa Campbell Menezes

Research Fellow

Takatoshi Chinen, PhD
Takatoshi Chinen

Postdoctoral Fellow

Ashutosh Chaudhry
Ashutosh Chaudhry

Research Scholar

Gabriel Loeb
Gabriel Loeb

MD/PhD Student

Saskia Hemmers, PhD
Saskia Hemmers

Research Associate

Bruno Moltedo, PhD
Bruno Moltedo

Research Associate

Jesse Green, PhD
Jesse Green

Postdoctoral Research Fellow

Dipayan Rudra, PhD
Dipayan Rudra

Postdoctoral Fellow

Nicholas Arpaia, PhD
Nicholas Arpaia

Postdoctoral Research Fellow

Sue Yee Lee

Research Technician

Paul DeRoos
Paul DeRoos

Research Technician

David Canner
David Canner

Research Technician

Julia Gerard
Julia Gerard

Research Technician

Wei Jin, PhD
Wei Jin

Postdoctoral Fellow

Steven Josefowicz
Steven Josefowicz

Graduate Research Assistant

Yuqiong Liang
Yuqiong Liang

Research Technician

Ling-li Lin

Research Technician

Li-Fan Lu
Li-Fan Lu

Research Fellow

Xiao Peng
Xiao Peng

Graduate Student

Yury Rubtsov
Yury Rubtsov

Research Associate

Robert Samstein
Robert Samstein

Graduate Student

Payam Zarin
Payam Zarin

Research Technician

Chrysothemis Brown
Chrysothemis Brown

Research Fellow

Deeksha Deep
Deeksha Deep

MD-PhD student

Bahawar S. Dhillon

Research Technician

Stanislav Dikiy
Stanislav Dikiy

Research Scholar

Shlomo Elias
Shlomo Elias

Research Fellow

Mehlika Faire
Xiying Fan

MD-PhD Student

Dan Feng

Research Fellow

Rachel Fromme
Rachel Fromme

Technician

Ariella Glasner
Ariella Glasner

Research Fellow

Jing Ping Hsin
Jing Ping Hsin

Research Fellow

Wei Hu, PhD
Wei Hu

Research Fellow

Catherine Konopacki, BS
Catherine Konopacki

Junior Analyst venBio Select Advisor New York, NY

Daniel Konstantinovsky
Daniel Konstantinovsky

Technician

Peter McKenney
Peter McKenney

Research Associate

Alejandra Mendoza
Alejandra Mendoza

Research Fellow

Sham Rampersaud

Research Technician

Michail Schizas
Michail Schizas

Bioinformatics Analyst

Melanie Smith

Research Fellow

Jared Theriot

Research Fellow, Department of Surgery

Izabella Valdez

Research Technician

Jacob Verter
Jacob Verter

Technician

Zhongmin Wang
Zhongmin Wang

Scientist 3, Immunology Discovery, Genentech, San Francisco, CA

Yi Zhong
Yi Zhong

Research Fellow

Lab Affiliations

Achievements

  • Investigator, Howard Hughes Medical Institute
  • Vilcek Prize in Biomedical Science, New York, NY (2018)
  • Crafoord Prize, the Royal Swedish Academy of Sciences, Stockholm Sweden (2017)
  • Member, National Academy of Medicine (2015)
  • Member, American Academy of Arts and Sciences (2015)
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  • Coley Award in Basic Immunology, Cancer Research Institute (2015)
  • Thomson Reuters Citation Laureate (2015)
  • Member, National Academy of Sciences (2012)
  • Merit Award, National Institutes of Health (2009)
  • Investigator Award, American Association of Immunologists/PharMingen (1999)
  • Searle Scholar Award (1993)
  • Investigator, Howard Hughes Medical Institute (1993)
  • Elucidation of the function of transcription factor Foxp3 in regulatory T cells and their critical role in immune homeostasis (2003-2010)
  • Identification of the primary structure of MHC class II bound peptides (1991)

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Alexander Rudensky discloses the following relationships and financial interests:

  • BioInvent International AB
    Professional Services and Activities
  • RAPT Therapeutics
    Equity; Professional Services and Activities
  • Santa Ana Bio, Inc.
    Equity; Professional Services and Activities
  • Sonoma Biotherapeutics, Inc.
    Equity; Professional Services and Activities
  • Surface Oncology
    Equity; Professional Services and Activities
  • Takeda Pharmaceuticals
    Intellectual Property Rights
  • Vedanta
    Equity; Professional Services and Activities

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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