and/or
60 News Items found
In the Clinic
Man and woman in white lab coats looking at test tubes
Single-Cell Analysis Enables Researchers to Understand the Differences within Tumors
Scientists are decoding the genetic changes that drive individual cancer cells. This may help them develop more-effective targeted therapies.
In the Clinic
Jedd Wolchok and Charlotte Ariyan in the lab
Chemotherapy-Immunotherapy Combination Aims to Knock Out Melanoma with a One-Two Punch
A new approach for treating melanoma combines the immunotherapy drug ipilimumab with chemotherapy that treats only the area affected by cancer.
In the Clinic
Medical oncologist Jae Park
Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects
The study represents 20 years of research at MSK.
Feature
A barred Plymouth Rock hen
How a Chicken Helped Solve the Mystery of Cancer
When this feathered patient found her way into a New York laboratory in 1909, she changed the course of cancer science.
Science Byte
Cancer biologist and pediatric oncologist Alex Kentsis
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers
A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.
Announcement
Pediatric oncologist Kevin Curran with CAR T patient Esmeralda Pineda
FDA Approves First CAR T Cell Therapy for Leukemia
Children, teens, and young adults with leukemia that have stopped responding to chemotherapy are the first eligible to receive the new treatment.
In the Lab
A scientist looks at illustrations of chromosomes.
When Loss Is a Gain: New Tumor Suppressor Gene Identified in Follicular Lymphoma
The reason certain patients with follicular lymphoma do worse than others may come down to a missing gene.
In the Lab
Images from three different mice showing the effects of antibiotics and microbiome replacement
Bacteria versus Bacteria: Two Studies Uncover Species of Microbes That Protect against Infections in People with Cancer
Research recently published by MSK scientists suggests that the best way to fight dangerous bacteria may be with other bacteria.
Finding
Grey T lymphocytes
#AACR17: Researchers Shed Light on Biological Activity of a New, First-in-Class Immunotherapy
A team at MSK uncovered how TRX518, a new immunotherapy drug in early development, works in the body.
In the Lab
CAR T cells attacking cancer
CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level
What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.
In the Lab
MSK scientists Charles Rudin and John Poirier
Scientists Home in on Treatment Advance for Chemotherapy-Resistant Small Cell Lung Cancer
An epigenetic mechanism may make small cell lung cancer vulnerable to a new kind of attack.
Feature
T cells on the loose.
T Is for T Cell: The Science Behind Immunotherapy
By deciphering the biology of T cells, MSK scientists gave immunotherapy a boost.
In the Lab
A chess match
Resistance Is Futile: Targeted Treatment Makes Stubborn Cancers Responsive to Immunotherapy
New research on an experimental drug provides hope for better responses to immunotherapy.
Announcement
Dr. Joan Massagué, Sloan Kettering Institute Director received the Pezcoller Foundation-AACR International Award for Cancer Research and was named an AACR fellow at AACR16.
News from #AACR16: Targeted Therapy Breakthrough, Improved Survival in Melanoma, and Benefits of Gut Bugs
Long-awaited results of clinical trials testing targeted drugs and immunotherapy combinations were on offer at the annual American Association for Cancer Research (AACR) conference.
In the Lab
a sneaky man on a sneaky mission
Stealth Mode: How Metastatic Cancer Cells Evade Detection by the Immune System
Cancer cells have a sneaky ability to hide out in the body for years at a time. MSK scientists are looking for ways to flush them out.
In the Lab
photo of Foxo1 protein stained in regulatory T cells
In the Fight against Cancer, the Immune System Can Be a Double-Edged Sword
The immune system is a powerful tool for fighting cancer — sometimes too powerful.
In the Lab
Light micrograph of white blood cells from a patient with acute myeloid leukemia.
New Drug Developed at MSK Starves Acute Myeloid Leukemia of a Signaling Fix
An innovative collaboration between basic scientists and clinical researchers has led to a promising new drug for AML.
Feature
Microscopic image of spherical cluster of cells, most of them pink cells with a smaller number of blue ones.
Three Compelling Cancer Advances from 2015
MSK researchers moved cancer science ahead in 2015 with landmark discoveries that suggest new treatment strategies and shed light on how the disease progresses.
In the Clinic
Hyperpolarized MRI
Hyperpolarized MRI: A New Tool to Assess Treatment Response within Days
Hyperpolarized MRI could allow doctors to get a read on a tumor’s response to treatment quickly.
In the Lab
MSK investigators Joan Massagué and Anna Obenauf
Outsmarting Cancer’s Survival Skills
A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.