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20 News Items found
In the Lab
Fluorescent image of CAR T cells in mouse liver fibrosis
A New Target for CAR T Cells: Senescence-Related Diseases
From atherosclerosis and diabetes to liver fibrosis and osteoarthritis, senescent cells are at the root of many debilitating diseases. Scientists increasingly have them in the crosshairs.
In the Clinic
Scientific Image
CAR Therapy for Solid Tumors Draws Attention at Annual Cancer Conference
Results from a clinical trial indicate that an experimental CAR therapy for mesothelioma is safe.
In the Lab
MSK Scientists Build "Armored" CAR T Cells to Smite Solid Tumors
The engineered immune cells secrete powerful drugs as a layer of defense.
Feature
MSK cell manufacturing specialist Xiuyan Wang
Meet the Scientists Who Engineer CAR T Cells, a Type of "Living" Immunotherapy
An immunotherapy called CAR T is transforming the treatment of certain cancers. These are the people who make it possible.
In the Lab
An illustration showing the process of CAR T cell therapy
Study Identifies New Way to Combat a Serious CAR T Cell Therapy Side Effect
By uncovering the root cause of cytokine release syndrome, MSK researchers have found a way to stop it.
Roundup
Sign for AACR scientific meeting featuring collage of images
Highlights from MSK at the 2018 American Association for Cancer Research Meeting
Read up on the latest developments in several key areas of cancer research, including genomic mapping, disease modeling through CRISPR, CAR T therapy, and cancer stem cells.
In the Lab
CAR T cells attacking cancer
CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level
What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.
In the Lab
Illustration of CAR T cells with conveyor belts leading out of them carrying HVEM protein in tablet form.
New Immunotherapy Approach Turns Cells into “Micro-Pharmacies”
A new immunotherapy approach involves engineering CAR T cells to produce proteins that treat lymphoma.
In the Clinic
CAR T cell therapy
CAR T Cell Therapies Are a Growing Area of Research
Cell therapies that use patients’ own immune cells to attack cancer — including CAR T cell therapy, an approach developed at MSK — are a promising and rapidly growing area of research.
In the Lab
Neurons created from embryonic stem cells
Seeing the Light: How Engineered Nerve Cells Might Curb Parkinson’s Disease
A new tool called optogenetics is revealing clues about the function of a promising experimental therapy derived from stem cells.
Finding
Michel Sadelain and Prasad Adusumilli
Immunotherapy Shows Promise for Treating Solid Tumors in the Chest
A study in mouse models suggests how modified T cells may be used to treat tumors in the area just outside the lungs.
In the Lab
Pictured: Experimental Brain Tumor
Genetic “Kill Switch” Could Make Cell Therapies Safer
Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.
MSK at ASCO
Pictured: Jedd Wolchok
Memorial Sloan Kettering’s Expertise in Cancer Immunotherapy Draws Media Focus at 2014 ASCO Meeting
Our experts offer their perspective in major media outlets on recent research into drug- and cell-based immunotherapies for cancer.
In the Clinic
New Trial Advances Cell-Based Immune Therapy for Certain Leukemias
A new study evaluating a cell-based immune therapy to treat an aggressive type of leukemia — the largest study of its kind to date — reports that 88 percent of patients responded to the treatment.
In the Lab
Pictured: Stem cell-derived nerve cells exposed to progerin
Researchers Fast-Forward Stem Cell Aging to Study Degenerative Diseases
A team of Memorial Sloan Kettering scientists has come up with an approach to make stem-cell-derived neurons rapidly age in a cell culture dish. The breakthrough could transform research into Parkinson’s and other late-onset diseases.
In the Clinic
Cell-Based Immune Therapy Shows Promise in Leukemia Patients
Memorial Sloan Kettering researchers have used genetically modified immune cells to eradicate cancer in five patients with acute lymphoblastic leukemia.
In the Lab
Pictured: Michel Sadelain
New Technique Could Make Cell-Based Immune Therapies for Cancer Safer and More Effective
Memorial Sloan Kettering researchers have reported a new method that could allow the development of more-specific, cell-based therapies for cancer.
Announcement
Pictured: Michel Sadelain & Jedd Wolchok
Memorial Sloan Kettering Researchers Appointed to Stand Up To Cancer Immunology “Dream Team”
Physician-scientists Michel Sadelain and Jedd Wolchok have been appointed to a new research team dedicated to investigating ways to harness the immune system to fight cancer.
Q&A
Pictured: Lorenz Studer
Developmental Biologist Lorenz Studer Comments on the 2012 Nobel Prize in Physiology or Medicine
Methods to generate stem cells have given scientists new ways to study some diseases and identify potential drugs, and could one day be used to rebuild diseased or damaged tissues in patients.
In the Clinic
Pictured: Isabelle Rivière and Michel Sadelain
Launch of Stem Cell Therapy Trial Offers Hope for Patients with Inherited Blood Disorder
Memorial Sloan Kettering’s trial to evaluate a new therapy for patients with beta-thalassemia is the first to receive FDA approval to treat this disease with genetically engineered cells.