I am an affiliate attending computer scientist in the Service of Predictive Informatics at MSK. I am also Distinguished Professor of Computer Science/Applied Mathematics at Stony Brook University. I have four decades of experience working in systems, computer vision, image processing, medical imaging computation, and biological networks. My research group and I have developed novel methodologies for segmentation, registration, and visualization, many of which have become state of the art in medical imaging. These include the first conformal geometric-based virtual colon flythrough, the first conformal method from brain flattening, and the application of optimal mass transport for image registration. I have been applying methods from mathematical network analysis to various biological problems, including cancer networks, with my research group at MSK.