Elena Elkin, PhD

Associate Attending Outcomes Research Scientist

Elena Elkin, PhD

Associate Attending Outcomes Research Scientist

Elena Elkin

Office Phone

646-888-8214

E-mail

elkine@mskcc.org

Current Research Interests

Dr. Elkin’s primary research interest is evaluating determinants of cancer screening, treatment and outcomes using population-based observational data analysis, decision analysis and patient surveys.  Her funded research agenda includes studies of the relationship between the availability of mammography resources and mammography utilization with a focus on geographic and racial disparities in access to and use of mammography; surveys of radiology facilities to assess access to screening mammography and access to low-dose chest CT for lung cancer screening; development and evaluation of a web-based decision aid for women ages 40-49 considering screening mammography; cost-effectiveness analysis of a patient-directed intervention to increase screening mammography in survivors of Hodgkin lymphoma; and studies of treatment patterns, complications, survival and costs in urologic cancers, gastrointestinal cancers and head and neck cancers in the population-based linked SEER-Medicare dataset.  Other research interests include studying the economic impact of cancer treatment on patients, their families and the health care system, and understanding and improving clinical decision-making processes from both patient and provider perspectives.

Education

Harvard University

Publications

Elkin EB, Hurria A, Mitra N, Schrag D, Panageas KS. Adjuvant chemotherapy and survival in older women with hormone receptor-negative breast cancer: assessing outcome in a population-based, observational cohort. J Clin Oncol, 2006; 24:2757-2764.

Elkin EB, Vickers AJ, Kattan MW. Primer: using decision analysis to improve clinical decision making in urology. Nat Clin Pract Urol. 2006; 3:439-448.

Elkin EB, Hudis C, Begg CB, Schrag DS, The effect of changes in tumor size on breast cancer survival in the U.S., 1975-1999. Cancer, 2005; 104:1149-57.

Elkin EB, Weinstein MC, Kuntz KM, Bunnell CA, Weeks JC. Adjuvant ovarian suppression versus chemotherapy for premenopausal, hormone-responsive breast cancer: quality of life and efficacy tradeoffs. Breast Cancer Res Treat, 2005; 93:25-34.

Elkin EB, Cowen ME, Cahill D, Steffel M, Kattan MW. Preference assessment method affects decision-analytic recommendations: A prostate cancer treatment example. Med Decis Making, 2004;24:504-510.

Elkin EB, Weinstein MC, Winer EP, Kuntz KM, Schnitt SJ, Weeks JC. HER-2 testing and trastuzumab therapy for metastatic breast cancer: A cost-effectiveness analysis. J Clin Oncol 2004; 22:854-63.

Elkin EB, Kim SHM, Casper ES, Kissane DW, Schrag D. Desire for information and involvement in treatment decisions: elderly cancer patients’ preferences and their physicians’ perceptions. J Clin Oncol 2007;25:5275-5280.

Read more

  1. Ruchlin HS, Elkin EB, Paget SA. Assessing cost-effectiveness studies in rheumatoid arthritis and osteoarthritis. Arthritis Care Res 1997;10:413-421. [PubMed Abstract]

  2. Ruchlin HS, Elkin EB, MacKenzie CR, Williams-Russo P, Allegrante JP. Determining the cost of a clinical intervention through the use of shadow pricing. Arthritis Care Res 1997;10:343­-351. [PubMed Abstract]

  3. Ruchlin HS, Elkin EB, Allegrante JP. The economic impact of a multifactorial intervention to improve postoperative rehabilitation of hip fracture patients. Arthritis Care Res 2001;45:446-52. [PubMed Abstract]

  4. Finkel ML and Elkin E. Trends in birth rates: New York City 1970-1995. J Community Health 2001;26:407-421. [PubMed Abstract]

  5. Heffner LJ, Elkin E, Fretts RC. Impact of labor induction, gestational age, and maternal age on cesarean delivery rates. Obstet Gynecol 2003;102:287-293. [PubMed Abstract]

  6. Elkin EB, Weinstein MC, Winer EP, Kuntz KM, Schnitt SJ, Weeks JC. HER-2 testing and trastuzumab therapy for metastatic breast cancer: A cost-effectiveness analysis. J Clin Oncol 2004; 22:854-63. [PubMed Abstract]

  7. Fretts RC, Elkin EB, Myers ER, Heffner LJ. Should older women have antepartum testing to prevent unexplained stillbirth? Obstet Gynecol 2004;104:56-64. [PubMed Abstract]

  8. Elkin EB, Cowen ME, Cahill D, Steffel M, Kattan MW. Preference assessment method affects decision-analytic recommendations: A prostate cancer treatment example. Med Decis Making, 2004;24:504-510. [PubMed Abstract]

  9. Bach PB, Elkin EB, Pastorino U, Kattan MW, Mushlin AI, Begg CB, Parkin DM. Benchmarking lung cancer mortality rates in current and former smokers. Chest, 2004;126:1742-1749. [PubMed Abstract]

  10. Saranchuk JW, Kattan MW, Elkin E, Touijer AK, Scardino PT, Eastham JA. Achieving optimal outcomes after radical prostatectomy. J Clin Oncol 2005;23:4146-4151. [PubMed Abstract]

  11. Panageas KS, Elkin EB, DeAngelis LM, Ben Porat L, Abrey LE. Trends in survival from primary central nervous system lymphoma 1975-1999: a population-based analysis. Cancer, 2005; 104:2466-2472. [PubMed Abstract]

  12. Elkin EB, Weinstein MC, Kuntz KM, Bunnell CA, Weeks JC. Adjuvant ovarian suppression versus chemotherapy for premenopausal, hormone-responsive breast cancer: quality of life and efficacy tradeoffs. Breast Cancer Res Treat, 2005; 93:25-34. [PubMed Abstract]

  13. Elkin EB, Hudis C, Begg CB, Schrag DS, The effect of changes in tumor size on breast cancer survival in the U.S., 1975-1999. Cancer, 2005; 104:1149-57. [PubMed Abstract]

  14. Schrag D, Xu F, Hanger M, Elkin E, Bickell NA, Bach PB. Fragmentation of care for frequently hospitalized urban residents. Med Care, 2006; 44:560-567. [PubMed Abstract]

  15. Elkin EB, Hurria A, Mitra N, Schrag D, Panageas KS. Adjuvant chemotherapy and survival in older women with hormone receptor-negative breast cancer: assessing outcome in a population-based, observational cohort. J Clin Oncol, 2006; 24:2757-2764. [PubMed Abstract]

  16. Vickers AJ, Elkin EB. Decision curve analysis: a novel method for evaluating prediction models. Med Decis Making, 2006; 26:565-574. [PubMed Abstract]

  17. Ballas LK, Elkin EB, Schrag D, Minsky BD, Bach PB.. Radiation therapy facilities in the United States. Int J Radiat Oncol Biol Phys, 2006; 66:1204-1211. [PubMed Abstract]

  18. Hurria A, Naeim A, Elkin EB, Limaye S, Grover A, Hudis C, Pearce C, Robson M. Adjuvant treatment recommendations in older women with breast cancer: a survey of oncologists. Crit Rev Oncol Hematol, 2007;61:255-260.

  19. Panageas KS, Elkin EB, Ben-Porat L, DeAngelis LM, Abrey LE. Patterns of treatment in older adults with primary central nervous system lymphoma. Cancer 2007;110:1338-1344.

  20. Elkin EB, Kim SHM, Casper ES, Kissane DW, Schrag D. Desire for information and involvement in treatment decisions: elderly cancer patients’ preferences and their physicians’ perceptions. J Clin Oncol 2007;25:5275-5280.

  21. Elkin EB, Ishill N, Riley GF, Bach PB, Gonen M, Begg CB, Schrag D. Disenrollment from Medicare managed care among beneficiaries with and without a cancer diagnosis. J Natl Cancer Inst, 2008;100:1013-1021.

  22. Kreisl TN, Panageas KS, Elkin EB, Deangelis LM, Abrey LE. Treatment patterns and prognosis in patients with human immunodeficiency virus and primary central system lymphoma. Leuk Lymphoma, 2008;49:1710-1716.

  23. Iwamoto FM, Reiner AS, Panageas KS, Elkin EB, Abrey LE. Patterns of care in elderly glioblastoma patients. Ann Neurol, 2008;64:628-34.

  24. Vickers AJ, Cronin AM, Elkin EB, Gonen M. Extensions to decision curve analysis, a novel method for evaluating diagnostic tests, prediction models and molecular markers. BMC Med Inform Decis Mak, 2008;8:53.

  25. Huang WC, Elkin EB, Levey AS, Jang TL, Russo P. Partial nephrectomy versus radical nephrectomy in patients with small renal tumors—is there a difference in mortality and cardiovascular outcomes? J Urol, 2009;181:55-61.

  26. Baxi SS, Liberman L, Lee C, Elkin EB. Breast imaging fellowships in the United States: Who, what and where? AJR Am J Roentgenol, 2009;192:403-407.

  27. Neuman HB, Elkin EB, Guillem JG, Paty PB, Weiser MR, Wong D, Temple LK. Treatment for patients with rectal cancer and a clinical complete response to neoadjuvant therapy: A decision analysis. Dis Colon Rectum (in press).

  28. Vickers AV, Elkin EB, Peele PB, Dickler M, Siminoff LA. Long-term health outcomes of a decision aid: Data from a randomized trial of Adjuvant! in women with localized breast cancer. Med Decis Making (in press).

  29. Phillips KA, Marshall DA, Haas JS, Elkin EB, Liang SY, Hassett MJ, Ferrusi I, Brock JE, Van Bebber SL. Clinical practice patterns and cost effectiveness of human epidermal growth receptor 2 testing strategies in breast cancer patients. Cancer, 2009;115:5166-5174.

  30. Iwamoto FM, Reiner AS, Nayak L, Panageas KS, Elkin EB, Abrey LE. Prognosis and patterns of care in elderly patients with glioma. Cancer, 2009;115:5534-5540.

  31. Lowrance WT, Elkin EB, Jacks LM, Yee DS, Jang TL, Laudone VP, MD, Guillonneau BD, Scardino PT, Eastham JA. Comparative effectiveness of surgical treatments for prostate cancer: A population-based analysis of postoperative outcomes. J Urol, 2010;183:1366-1372.

  32. Elkin EB, Ishill NM, Snow JG, Panageas KS, Bach PB, Liberman L, Wang F, Schrag D. Geographic access and the use of screening mammography. Med Care, 2010;48:349-356.

  33. Jang TL, Bekelman JE, Liu Y, Bach PB, Basch EM, Elkin EB, Zelefsky MJ, Scardino PT, Begg CB, Schrag D. Physician visits prior to treatment for clinically localized prostate cancer. Arch Intern Med, 2010; 170:440-450.

  34. Elkin EB, Bach PB. Cancer’s next frontier: addressing high and increasing costs. JAMA, 2010;303:1086-1087.

  35. Ito K, Elkin EB, Girotra M, Morris JM. Cost-effectiveness of fracture prevention in men receiving androgen deprivation therapy for localized prostate cancer. Ann Intern Med, 2010;152:621-629.

  36. Baxi SS, Snow JG, Liberman L, Elkin EB. The future of mammography: Radiology residents’ experiences, attitudes and opinions. AJR Am J Roentgenol, 2010;194:1680-1686.

  37. Morrogh M, Park A, Elkin EB, King TA. Lessons learned from 416 cases of nipple discharge of the breast. Am J Surg, 2010; 200:73-80.

  38. Elkin EB, Klem ML, Gonzales AM, Ishill NM, Hodgson D, Ng AK, Marks LB, Weidhaas J, Freedman G, Robert C. Miller, Constine LS, Myrehaug S, Yahalom J. Characteristics and outcomesof breast cancer in women with and without a history of radiation for Hodgkin lymphoma: A multi-Institutional matched cohort study. J Clin Oncol, 2011 J Clin Oncol;29:2466-2473.

  39. Boscoe FP, Johnson CJ, Henry KA, Goldberg DW, Shahabi K, Elkin EB, Ballas LK, Cockburn M.Geographic proximity to treatment for early stage breast cancer and likelihood of mastectomy. Breast,2011 [Epub ahead of print]

  40. Feifer AH, Elkin EB, Lowrance WT, Denton B, Jacks L, Yee DS, Coleman JA, Laudone VP, Scardino PT, Eastham JA. Temporal trends and predictors of pelvic lymph node dissection in open or minimally invasive radical prostatectomy. Cancer, 2011;117:3933-3942.

  41. Haas JS, Phillips KA, Liang SY, Hassett MJ, Keohane C, Elkin EB, Armstrong J, Toscano M. Genomic testing and therapies for breast cancer in clinical practice. Am J Manag Care, 2011;17(5 Spec No):e174-181.

  42. Haas JS, Phillips KA, Liang SY, Hassett MJ, Keohane C, Elkin EB, Armstrong J, Toscano M. Genomic testing and therapies for breast cancer in clinical practice. J Oncol Pract. 2011;7(3 Suppl):e1s-7s.

  43. Ladabaum U, Wang G, Terdiman J, Blanco A, Kuppermann M, Boland CR, Ford J, Elkin E, Phillips KA. Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. Ann Intern Med. 2011;155:69-79.

  44. Tal R, Jacks LM, Elkin E, Mulhall JP. Penile implant utilization following treatment for prostate cancer: Analysis of the SEER-Medicare database. J Sex Med, 2011;8:1797-1804.

  45. Yee DS, Ishill NM, Lowrance WT, Herr HW, Elkin EB. Ethnic differences in bladder cancer survival. Urology, 2011;78:544-549.

  46. Elkin EB, Marshall DA, Kulin NA, Ferrusi IL, Hassett MJ, Ladabaum U, Phillips KA, Economic evaluation of targeted cancer interventions: Critical review and recommendations. Genetics in Medicine, 2011;13:853-860.

  47. Haas JS, Liang SY, Hassett MJ, Shiboski S, Elkin EB, Phillips KA. Gene expression profile testing for breast cancer and the use of chemotherapy, serious adverse effects, and costs of care. Breast Cancer Res Treat, 2011;130:619-626.

  48. Karanicolas PJ, Elkin EB, Jacks LM, Atoria CL, Strong VE, Brennan MF, Coit DG. Staging laparoscopy in the management of gastric cancer: A population-based analysis. J Am Coll Surg, 2011;213:644-651.

  49. Elkin EB, Snow JG, Leoce NM, Atoria CL, Schrag D. Mammography capacity and appointment wait times: Barriers to breast cancer screening. Cancer Causes Control, 2012;23:45-50.

  50. Mirkin JN, Lowrance WT, Feifer AH, Mulhall JP, Eastham JE, Elkin EB. Direct-to-consumer internet promotion of robotic prostatectomy exhibits varying quality of information. Health Aff, 2012;31:760-769.

  51. Olson SH, Atoria CL, Cote ML, Cook LS, Rastogi R, Soslow RA, Brown CL, Elkin EB. The impact of race and comorbidity on survival in endometrial cancer. Cancer Epidemiol Biomarkers Prev, 2012; 21:753-760.

  52. Lowrance WT, Elkin EB, Yee DS, Feifer A, Ehdaie B, Jacks LM, Atoria CL, Zelefsky MJ, Scher HI, Scardino PT, Eastham JA. Locally advanced prostate cancer: a population-based study of treatment patterns. BJU Int, 2012; 109:1309-1314.

  53. Lowrance WT, Eastham JA, Yee DS, Laudone VP, Denton B, Scardino PT, Elkin EB. Costs of medical care after open or minimally invasive prostate cancer surgery: A population-based analysis. Cancer, 2012;118:3079-3086.

  54. Ito K, Blinder VS, Elkin EB. Cost effectiveness of fracture prevention in postmenopausal women who receive aromatase inhibitors for early breast cancer. J Clin Oncol, 2012;30:1468-1475.

  55. Ehdaie B, Atoria CL, Gupta A, Feifer A, Lowrance WT, Morris MJ, Scardino PT, Eastham JA, Elkin EB. Androgen deprivation and thromboembolic events in men with prostate cancer. Cancer, 2012;118:3397-3406.

  56. O’Neill CB, Atoria CL, O’Reilly EM, Lafemina J, Henman MC, Elkin EB. Costs and trends in pancreatic cancer treatment. Cancer, 2012;118:5132-5139.

  57. Elkin EB, Shapiro E, Snow JG, Zauber AG, Krauskopf MS. The economic impact of a patient navigator program to increase screening colonoscopy. Cancer, 2012;118:5982-5988.

  58. Kim PH, Pinheiro LC, Atoria CL, Eastham JA, Sandhu JS, Elkin EB. Trends in the use of incontinence procedures after radical prostatectomy: A population-based analysis. J Urol, 2013;189:602-608.

BOOKS, BOOK CHAPTERS, REVIEWS


  1. Ruchlin HS, Elkin EB. Economic considerations in the care of patients with head and neckmalignancies. Curr Opin Oncol 1997;9:241-246.

  2. Pfister DG, Ruchlin HS, Elkin EB. Health services research in head and neck cancer. In CL Bennettand TS Pajeau (Eds.) Cancer Policy: Research and Methods. Boston: Kluwer Academic, 1998.

  3. Elkin EB, Vickers AJ, Kattan MW. Primer: using decision analysis to improve clinical decision making in urology. Nat Clin Pract Urol. 2006; 3:439-448. [PubMed Abstract]

  4. Elkin EB and Blinder VS. Advances in breast cancer: Reducing risk and improving health outcomes. In ML Finkel (Ed), Perspectives in Public Health: Challenges for the 21st Century. Santa Barbara, CA: Praeger, 2010.

LETTERS AND EDITORIALS


  1. Vickers AJ, Elkin EB, Steyerberg E. Net reclassification improvement and decision theory. Stat Med, 2009;28:525-526.

  2. Lowrance WT, Elkin EB, Scardino PT, Eastham JA. Words of wisdom. Re: Comparative effectiveness of minimally invasive vs open radical prostatectomy. Eur Urol, 2010;57:538.

  3. Lowrance WT, Elkin EB, Eastham JA. Minimally invasive vs open radical prostatectomy (letter to the editor). JAMA, 2010;303:619-620.