Dr. Patil’s biostatistical research interests are in longitudinal data analysis, clinical trial design, the analysis of incomplete data, survival analysis, measurement error models, and Bayesian methods. Dr. Patil uses these methods in her clinical collaborations with oncologists and surgeons in the Genitourinary, Breast, and Colorectal Surgery Services. In recent publications, she has examined stage migration in metastatic renal cell carcinoma over the last four decades. In ongoing work, Dr. Patil is developing methodology that can be used to investigate the relationship between two or more longitudinal biomarkers as predictors of disease outcome. Recently, she has been involved in developing efficient clinical trial designs for therapies that target brain metastases. Dr. Patil regularly lectures for the Department of Surgery Clinical Research Methods course and for the Department of Medicine K30 Clinical Trial Design Symposium.
Patil S, Figlin RA, Hutson TE, Michaelson MD, Négrier S, Kim ST, Huang X, Motzer RJ. Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma. Ann Oncol. 2011 Feb;22(2):295-300. Epub 2010 Jul 25. [PubMed Abstract]
Patil S, Ishill N, Deluca J, Motzer RJ. Stage migration and increasing proportion of favorable-prognosis metastatic renal cell carcinoma patients: implications for clinical trial design and interpretation. Cancer. 2010 Jan 15;116(2):347-54. [PubMed Abstract]
Bosl GJB, Patil SM. Carboplatin in clinical stage I seminoma: too much and too little at the same time. J Clin Oncol. 2011 Jan 31. [PubMed Abstract]
Patil S, Figlin RA, Hutson TE, Michaelson MD, Negrier S, Kim ST, Huang X, Motzer RJ. Q-TWiST analysis to estimate overall benefit for patients with metastatic renal cell carcinoma treated in a phase III trial of sunitinib versus interferon-alfa. British Journal of Cancer. [in press]
Patil SM, Shope JT, Raghunathan TE, Bingham CR. The role of personality characteristics in young adult driving. Traffic Inj Prev. 2006 Dec;7(4):328-34. [PubMed Abstract]