Recent MSK Discoveries & Advances

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Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our blog, On Cancer.

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450 News Items found
In the Lab
An illustration of sugar being sprinkled on a cancer cell.
Just Add Sugar: How a Protein’s Small Change Leads to Big Trouble for Cells
A study from investigators in the Sloan Kettering Institute uncovers the details of how a key protein called GRP94 becomes disrupted, leading to cancer and other diseases.
In the Lab
Confocal microscopy image of a female fruit fly brain.
How Fruit Flies Know When They've Mated
Research from investigators at the Sloan Kettering Institute shows how a brain circuit controls mating behavior in fruit flies.
In the Lab
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target
New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
In the Lab
Fluorescent image of CAR T cells in mouse liver fibrosis
A New Target for CAR T Cells: Senescence-Related Diseases
From atherosclerosis and diabetes to liver fibrosis and osteoarthritis, senescent cells are at the root of many debilitating diseases. Scientists increasingly have them in the crosshairs.
In the Lab
X and Y chromosomes in mice
Breaking Up Is Hard to Do (Especially for Sex Chromosomes)
One’s big, one’s small. Somehow, they make it work.
Feature
Two gloved hands opening a drawer in a laboratory.
Double Trouble: Researchers Find Many Cancers Carry Two Mutations in the Same Gene
Discovery reveals that the genetic causes of cancer may be more complicated than previously thought.
In Brief
A fluorescent image of cells undergoing differentiation in a mouse model.
Cancer Stem Cells’ Reliance on a Key Amino Acid Could Be an Exploitable Weakness
The discovery links metabolism to the way cancer stem cells form tumors.
In the Lab
Chromosomes from a human male
How Small Chromosomes Compete with Big Ones for a Cell’s Attention
During meiosis, small chromosomes risk being lost in the shuffle. Here’s how they hold their own.
Feature
Paul Chapman with a patient
A Changing Melanoma Landscape: How Research Has Improved the Outlook for People with Advanced Disease
Learn about how research led by MSK clinical investigators has transformed the treatment of metastatic melanoma.
In the Lab
Fluorescent image of mouse prostate gland
New Discovery Explains How the Prostate Gland Regenerates Itself
Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found.