My lab studies gene regulation during development and cancer, with a focus on the regulation and function of alternative 3’UTRs.
We recently discovered that alternative 3’UTRs can determine protein localization and protein function. They do so by acting as scaffolds to allow co-translational protein complex formation.
Christine Mayr, MD, PhD
Research FocusMolecular biologist Christine Mayr studies how the noncoding parts of transcription units (3’UTRs) determine protein function and protein localization.
- MD, Free University Berlin
- PhD, Humboldt University Berlin
- Berkovits BD, Mayr C. Alternative 3’UTRs act as scaffolds to regulate membrane protein localization. Nature (2015). Epub 2015 Apr 20.
- Lianoglou S, Garg V, Yang JL, Leslie CS, Mayr C. Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression. Genes Dev, 2013. Published in Advance October 21, 2013, doi:10.1101/gad.229328.113
- Pershing Square Sohn Prize for Young Investigators in Cancer Research (2015)
- Damon Runyon-Rachleff Innovation Award, Damon Runyon Cancer Research Foundation (2012)
- Kimmel Scholar Award, Sidney Kimmel Foundation (2011)