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Group Meeting Papers 2011

Here is a list of research papers that have been presented for discussion in our weekly group meetings. Papers are selected by group members as a means to broaden our knowledge in chemistry and chemical biology.

19 Dec 2011, presented by Todd Wenderski
Enantioselective total synthesis of (–)-acetylaranotin, a dihydrooxepine epidithiodiketopiperazine.
Codelli, J. A.; Puchlopek, A. L. A.; Reisman, S. E.* J. Am. Chem. Soc 2012, 134, 1930–1933.
Abstract ]

5 Dec 2011, presented by Jeff Rothman
Ligand preorganization may be accompanied by entropic penalties in protein–ligand interactions.
Benfield, A. P.; Teresk, M. G.; Plake, H. R.; DeLorbe, J. E.; Millspaugh, L. E.; Martin, S. F.* Angew. Chem. Intl. Ed. 2006, 45, 6830–6835.
Abstract ]

31 Oct 2011, presented by Tony Davis
Collective synthesis of natural products by means of organocascade catalysis.
Jones, S. B.; Simmons, B.; Mastracchio, A.; MacMillan, D. W. C.* Nature 2011, 475, 183–188.
Abstract ]

17 Oct 2011, presented by Debarshi Pratihar
A convergent strategy for the synthesis of polycyclic ethers by using oxiranyl anions.
Sakai, T.; Sugimoto, A.; Mori, Y.* Org. Lett. 2011, 13, 5850–5853.
Abstract ]

6 Sep 2011, presented by Felix Kopp
Three-component coupling of arynes and organic bromides.
Yoshida, H.;* Asatsu, Y.; Mimura, Y.; Ito, Y.; Ohshita, J.; Takaki, K. Angew. Chem. Intl. Ed 2011, 50, 9676–9679.
Abstract ]

22 Aug 2011, presented by Chris Stratton
Total synthesis of N-methylwelwitindolinone D isonitrile.
Bhat, V.; Allan, K. M.; Rawal, V. H.* J. Am. Chem. Soc. 2011, 133, 5798–5801.
Abstract ]

Total synthesis of (–)-N-methylwelwitindolinone C isothiocyanate.
Huters, A. D.; Quasdorf, K. W.; Styduhar, E. D.; Garg, N. K.* J. Am. Chem. Soc 2011, 133, 15797–157999.
Abstract ]

1 Aug 2011, presented by Renato Bauer
Regioselective reactions for programmable resveratrol oligomer synthesis.
Snyder, S. A.*; Gollner, A.; Chiriac, M. I.Nature 2011, 474, 461–466.
Abstract ]

11 Jul 2011, presented by Felix Kopp
Branching cascades: A concise synthetic strategy targeting diverse and complex molecular frameworks .
Liu, W.; Khedkar, V.; Baskar, B.; Schürmann, M.; Kumar, K.* Angew. Chem. Intl. Ed. 2011, 50, 6900–6905.
Abstract ]

20 Jun 2011, presented by Inder Sharma
Total synthesis of the cyanolide A aglycon.
Gesinksi, M. R.; Rychnovsky, S. D.* J. Am. Chem. Soc. 2011, 133, 9727–9729.
Abstract ]

13 Jun 2011, presented by Todd Wenderski
A concise, stereocontrolled total synthesis of rippertenol.
Snyder, S. A.*; Wespe, D. A.; von Hof, J. M. J. Am. Chem. Soc. 2011, 133, 8850–8853.
Abstract ]

11 Apr 2011, presented by Tony Davis
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis.
Backus, K. M.; Boshoff, H. I.; Barry, C. S.; Boutureira, O.; Patel, M. K.; D’Hooge, F.; Lee, S. S.; Via, L. E.; Tahlan, K.; Barry III, C. E.*; Davis, B. G.* Nat. Chem. Biol. 2011, 7, 228–235.
Abstract ]

8 Mar 2011, presented by Debarshi Pratihar
11-Step enantioselective synthesis of (-)-lomaiviticin aglycon.
Herzon, S. B.*; Lu, L.; Woo, C. M.; Gholap, S. L. J. Am. Chem. Soc. 2011, 133, 7260–7263.
Abstract ]

15 Feb 2011, presented by Gustavo Moura-Letts
Expeditious onstruction of a carbobicyclic skeleton via sp³-C−H functionalization: Hydride shift from an aliphatic tertiary position in an internal redox process..
Mori, K.; Sueoka, S.; Akiyama, T.* J. Am. Chem. Soc. 2011, 133, 2424–2426.
Abstract ]

24 Jan 2011, presented by Chris Stratton
Diversity-oriented synthesis of polycyclic scaffolds by modification of an anodic product derived from 2,4-dimethylphenol.
Barjau, J.; Schnakenburg, G.; Waldvogel, S. R.* Angew. Chem. Intl. Ed. 2011, 50, 1415–1419.
Abstract ]

11 Jan 2011, presented by Jackie Wurst
Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles.
Clemons, P. A.; Bodycombe, N. E.; Carrinski, H. A.; Wilson, J. A.; Shamji, A. F.; Wagner, B. K.; Koehler, A. N.; Schreiber, S. L.* Proc. Natl. Acad. Sci. USA 2010, 107, 18787–18792.
Abstract ]