In our laboratory, we employ in-depth, state-of-the-art genome interrogation studies to understand the molecular origins and corresponding clonal relationships in cancer, as well as how these determine clinical phenotype and response to therapy. Our mission is to execute research that informs clinical practices in oncology and moves them forward. To achieve this, we conduct systematic research of large patient cohorts to extract genotype-outcome relationships, perform detailed clonal heterogeneity tracking studies in select clinical trial cohorts, and explore distinct genetic associations with emerging single-cell and iPS profiling methodologies.

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Eli Papemmanuil

Elli Papaemmanuil, PhD

Associate Professor

Research Focus

Molecular geneticist Elli Papaemmanuil performs systematic interrogations of well annotated clinical trial cohorts in leukemia and cancer to explore how the compound genetic and clonal architecture in patients leukemias and tumors dictate clinical phenotype, disease progression and clinical outcomes.


PhD – University of London, London, England, UK

Lab Members

Selected Achievements

  • European Hematology Association Young Investigator Award
  • Cancer Research UK Career Development Award

Career Opportunities

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