Our laboratory investigates innate and adaptive immune responses to infection by microbes, with a particular focus on the role of the intestinal microbiota and the mucosal immune system in preventing infections by antibiotic-resistant bacterial pathogens. We study the role of specific commensal bacterial species in providing resistance against Vancomycin-resistant Enterococcus, highly antibiotic-resistant Klebsiella pneumoniae and Clostridium difficile.
Eric G. Pamer, MD
Research FocusPhysician-scientist Eric Pamer studies T cell and innate inflammatory responses to bacterial and fungal infections.
EducationMD, Case Western Reserve University School of Medicine
- van Heijst JW, Ceberio I, Lipuma LB, Samilo DW, Wasilewski GD, Gonzales AM, Nieves JL, van den Brink MR, Perales MA, Pamer EG. Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation. Nat Med. 2013 Mar;19(3):372-7. doi: 10.1038/nm.3100. Epub 2013 Feb 24.
- Ubeda C, Bucci V, Caballero S, Djukovic A, Toussaint NC, Equinda M, Lipuma L, Ling L, Gobourne A, No D, Taur Y, Jenq RR, van den Brink MR, Xavier JB, Pamer EG. Intestinal microbiota containing Barnesiella species cures vancomycin-resistant Enterococcus faecium colonization. Infect Immun. 2013 Mar;81(3):965-73. doi: 10.1128/IAI.01197-12. Epub 2013 Jan 14.
- Member, Association of American Physicians (2011)
- Fellow, Infectious Diseases Society of America (2010)
- Member, American Society for Clinical Investigation (1998)
- Pew Scholar in the Biomedical Sciences, Pew Charitable Trust (1994)