Chemical Biology Program
The Heeseon An Lab
Research
Human cells orchestrate up to ~20,687 proteins to maintain cell growth and survival. Upon environmental change, cells dynamically remodel their proteomic landscape by two simultaneous processes: enhancing the synthesis of proteins that respond to the altered cellular conditions and degrading a subset of the pre-existing proteome. Any defect in this nature’s fine-tuned system hampers regulated cell growth as exemplified by cancer and neurodegenerative disorders. To fully understand the underlying pathology of the dysregulated proteostasis system, Heeseon An’s lab studies the regulatory mechanisms of protein translation and degradation processes in health and disease. Importantly, we develop chemical, biological, and proteomics tools to enable quantitative analyses of the cell biological events.
People
Heeseon An, PhD
- Heeseon An’s lab studies protein degradation in health and disease using chemical, biological, and proteomics tools.
- BS and MS, Chemistry, Seoul National University
- PhD, Chemistry, Northwestern University
- Postdoc, Cell Biology, Harvard Medical School
- [email protected]
- Email Address
- 646-888-3417 (ZRC-2003)
- Office Phone
- Download CV
- PDF File
Members
Post-doctoral Fellow
Post-doctoral Fellow
WCM Pharm graduate student
TPCB graduate student
WCM Pharm graduate student
TPCB graduate student
TPCB graduate student
Administrative Assistant
Lab Alumni
Administrative Assistant
