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The Jerard Hurwitz Lab: Publications

Visit PubMed for a full listing of Jerard Hurwitz’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Yardimci H, Wang X, Loveland AB, Tappin I, Rudner DZ, Hurwitz J, van Oijen AM, Walter JC. Bypass of a protein barrier by a replicative DNA helicase. Nature. 2012 Dec 13;492(7428):205-9. doi: 10.1038/nature11730. Epub 2012 Nov 28.

Bermudez VP, Farina A, Higashi TL, Du F, Tappin I, Takahashi TS, Hurwitz J. In vitro loading of DNA by the human Scc2-Sc4 complex. Proc Natl Acad Sci USA. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9366-71. doi: 10.1073/pnas. 1206840109. Epub 2012 May 24.

Fu YV, Yardimci H, Long DT, Ho TV, Guainazzi A, Bermudez VP, Hurwitz J, van Oijen A, Schärer OD, Walter JC.  Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase. Cell. 2011 Sep 16;146(6):931-41. doi: 10.1016/j.cell.2011.07.045.

Bermudez VP, Farina A, Raghavan V, Tappin I, Hurwitz J. Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication. J Biol Chem. 2011 Aug 19;286(33):28963-77. doi: 10.1074/jbc.M111.256289. Epub 2011 Jun 24.

Bermudez VP, Farina A, Tappin I, Hurwitz J. Influence of the cohesion establishment factor human Ctf4/AND-1 on DNA replication. J Biol Chem. 2010 Mar 26;285(13):9493-505. doi: 10.1074/jbc.M109.093609. Epub 2010 Jan 19.

Giordano-Coltart J, Ying CY, Gautier J and Hurwitz J. Studies of the properties of human origin recognition complex and its Walker A motif mutants. Proc Natl Acad Sci USA 2005; 102:69-74.

Gaczynska M, Osmulski PA, Jiang Y, Lee JK, Bermudez V and Hurwitz J. Atomic force microscopic analysis of the binding of the Schizosaccharomyces pombe origin recognition complex and the spOrc4 protein with origin DNA. Proc Natl Acad Sci USA 2004; 101:17952-7.

Fien K, Cho Y-S, Lee J-K, Raychaudhuri S, Tappin I, and Hurwitz J. Primer Utilization by DNA Polymerase a-Primase is Influenced by Its Interaction withMcm10p. J Biol Chem 2004; 279:16144-16153.

BermudezVP, Maniwa Y, Tappin I, Ozato K, Yokomori K and Hurwitz J. The alternative Ctf18-Dcc1-Ctf8-RFC complex required for sister chromatid cohesion loads PCNA onto DNA. Proc Natl Acad Sci USA 2003; 18:10237-10242.

Shin JH, Jiang Y, Grabowski B, Hurwitz J, Kelman Z. Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases. J Biol Chem. 2003; 278:49053-62.

Kelman Z, Hurwitz J. Structural lessons in DNA replication from the third domain of life. Nat Struct Biol. 2003; 10:148-50.

Lee JK, Seo YS, Hurwitz J. The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase. Proc Natl Acad Sci U S A. 2003; 100:2334-9.

Bermudez VP, Lindsey-Boltz LA, Cesare AJ, Maniwa Y, Griffith JD, Hurwitz J, Sancar A. Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc Natl Acad Sci U S A. 2003; 100:1633-8.