The Kim lab is interested in the role that epigenetic regulation plays in pluripotency and cancer. Specifically, we are using comparative methylome studies to assess genome-wide patterns of methylation in cells derived from various tissue types and donors, including pluripotent stem cells generated via multiple methodologies. The goal of these studies is to identify the mechanisms that regulate DNA methylation and to define their contribution to the cell’s ability to self-renew, differentiate, and function normally.
Kitai Kim, PhD
Research FocusStem cell biologist Kitai Kim studies epigenetic regulation of DNA methylation in stem cells and cancer.
- PhD, University of Wisconsin
- Tahmasebi S, Alain T, Vinagolu KR, Zhang JP, Prager-Khoutorsky M, Khoutorsky A, Dogan Y, Gkogkas CG, Petroulakis E, Sylvestre A, Assadian S, Yamanaka Y, Vinagolu-Baur JR, Teodoro JG, Kim K, Yang XJ, and Sonenberg N. Multifaceted regulation of somatic cell reprogramming by mRNA translational control. Cell Stem Cell. 14(5):606-616 (2014)
- Sumer H, Kim K, Liu J, Ng K, Daley GQ, and Verma PJ. Functional evaluation of ES-somatic cell hybrids in vitro and in vivo. Cellular Reprogramming. 16(3):167-74 (2014) Sumer H and Kim K share co-first-authorship.