Memorial Hospital Research Laboratories

The Margaret Callahan Lab

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Research

Margaret K. Callahan, MD, PhD
Margaret Callahan, MD, PhD
Associate Attending

As a clinician-scientist, immunologist, and practicing medical oncologist, I have focused my career on understanding how the immune system may be modified to improve outcomes in patients with cancer. Together with Drs. Shen and Panageas, I lead a research program that seeks to uncover the clinical relevance of immunologic characteristics of patients and tumors.

Featured News

MSK scientists Margaret Callahan, Ronglai Shen, and Katherine Panageas
MSK Study Identifies Biomarker That May Help Predict Benefits of Immunotherapy

A blood-based test identifies patients in whom immunotherapy may ‘LAG.’
Finding
A young female doctor in a white coat sits with an older male patient in an exam room
Uncertainties about Clinical Trials Keep Patients from Enrolling

Most people are aware of how important clinical trials for cancer are and how they can lead to lifesaving breakthroughs, but they’re also unlikely to participate in them.

Publications

Shen R, Postow MA, Adamow M, Arora A, Hannum M, Maher C, Wong P, Curran MA, Hollmann TJ, Jia L, Al-Ahmadie H, Keegan N, Funt SA, Iyer G, Rosenberg JE, Bajorin DF, Chapman PB, Shoushtari AN, Betof AS, Momtaz P, Merghoub T, Wolchok JD, Panageas KS, Callahan MK. LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade. Sci Transl Med. 2021 Aug 25;13(608):eabf5107. doi: 10.1126/scitranslmed.abf5107. PMCID: PMC9254663.

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People

Margaret K. Callahan, MD, PhD

Margaret Callahan, MD, PhD

Associate Attending

  • Physician-scientist Maggie Callahan studies how the characteristics of the immune system relate to clinical outcomes for patients who receive immunotherapy as a treatment for their cancer.
[email protected]
Email Address

Members

Matthew Adamow
Matthew Adamow

Technical Research Specialist

Fiona Ehrich
Fiona Ehrich

Assistant Research Biostatistician

Jasme Lee
Jasme Lee

Research Biostatistician

Colleen Maher

Senior Project Manager

Katherine Panageas, DrPH
Katherine Panageas

Attending Biostatistician; Director, Research Support

peng
Xiyu Peng

Research Fellow

Ronglai Shen, PhD
Ronglai Shen

Attending Biostatistician

James W. Smithy
Lab Affiliations

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Margaret Callahan discloses the following relationships and financial interests:

  • AstraZeneca
    Professional Services and Activities
  • Axios
    Professional Services and Activities
  • Bristol-Myers Squibb
    Professional Services and Activities (Uncompensated)
  • Celldex Therapeutics
    Professional Services and Activities
  • Clinical Care Options
    Professional Services and Activities
  • Daiichi Sankyo
    Professional Services and Activities
  • Immunocore
    Professional Services and Activities
  • Incyte
    Professional Services and Activities
  • Merck & Co Inc.
    Professional Services and Activities
  • Moderna, Inc.
    Professional Services and Activities

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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