More About The Derek Tan Lab Minus iconIcon indicating subtraction, or that the element can be closed. Plus IconIcon indicating addition, or that the element can be opened. Arrow (down) icon.An arrow icon, usually indicating that the containing element can be opened and closed.

Cheng Ji, PhD

Postdoctoral Fellow

Cheng Ji, PhD

Lab Phone


Lab Fax

646-422-0416 (shared)

Senior Scientist, 2015-present
Chicago, Illinois

PhD, University of Notre Dame, 2012

BS, Nanjing University, 2007


  • Designed small-molecule inhibitors of the Anthranilyl-CoA synthetase PqsA block quinolone biosynthesis in Pseudomonas aeruginosa.
    Cheng J.; Sharma, I. ; Pratihar, I.;Hudson, L.; Maura, D.; Guney, T.; Rahme, L. G.; Pesci, E. C.; Coleman, J. P.; Tan, D. S.*; ACS Chem. Biol. 2016
    Abstract | PubMed ]

  • Iron transport-mediated drug delivery: Practical syntheses and in vitro antibacterial studies of tris-catecholate siderophore-aminopenicillin conjugates reveals selectively potent antipseudomonal activity.
    Ji, C.; Miller, P. A.; Miller, M. J.* J. Am. Chem. Soc. 2012, 134, 9898–9901.
    Abstract | PubMed ]

  • Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers.
    Ji, C.; Miller, M. J.* Bioorg. Med. Chem. 2012, 20, 3828–3836.
    Abstract | PubMed ]

  • Syntheses and biological studies of novel spiropiperazinyl oxazolidinone antibacterial agents using a spirocyclic diene derived acylnitroso Diels−Alder reaction.
    Ji, C.; Lin, W.; Moraski, G. C.; Thanassi, J. A.; Pucci, M. J.; Franzblau, S. G.; Möllmann, U.; Miller, M. J.* Bioorg. Med. Chem. 2012, 20, 3422–3428.
    Abstract | PubMed ]

  • Exploiting bacterial iron acquisition: Siderophore conjugates.
    Ji, C.; Juárez-Hernández R. E.; Miller, M. J.* Future Med. Chem. 2012, 4, 297–313.
    Abstract | PubMed ]

  • Reactivity of the 16e (p-cymene)Ru half-sandwich complex containing a chelating 1,2-dicarba-closo-dodecaborane-1,2-dithiolate ligand towards diynes .
    Xu, Z. W.; Han, L.; Ji, C.; Zhang, R.; Shen, X. J.; Yan, H.* Dalton Trans. 2011, 40, 6992–6997.
    Abstract | PubMed ]

  • Cyclopropanation of nitroso Diels–Alder cycloadducts and application to the synthesis of a 2′,3′-methano carbocyclic nucleoside.
    Ji, C.; Miller, M. J.* Tetrahedron Lett. 2010, 51, 3789–3791.
    Abstract | PubMed | PMC ]

  • A novel dinuclear ruthenium(I)/ruthenium(III) half-sandwich complex containing two chelating 1,2-dicarba-closo-dodecaborane-1,2-dithiolate ligands and its reactivity with alkynes.
    Wu, D. H.; Ji, C.; Li, Y. Z.; Yan, H.* Organometallics 2007, 26, 1560–1562.
    Abstract ]

  • Obacunone.
    Zhou, X.; Ji, C.; Fu, J.; Li, Y. G.* Acta Crystallogr., Sect. E: Struct. Rep. Online 2006, 62, O5544–O5546.
    Abstract ]