My research interests lie at the interface of computational immunology, cancer, mathematical modeling, and evolution.
D. Chowell et al., TCR contact residue hydrophobicity is a hallmark of immunogenic CD8(+) T cell epitopes. Proceedings of the National Academy of Sciences of the United States of America 112, E1754-E1762 (2015).
D. Chowell et al., Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy. Science (2017).
D. Chowell et al., Modeling the subclonal evolution of cancer cell populations. Cancer Research (2017).
N. Riaz et al., Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab. Cell (2017).