More About The Jedd Wolchok Lab Minus iconIcon indicating subtraction, or that the element can be closed. Plus IconIcon indicating addition, or that the element can be opened. Arrow (down) icon.An arrow icon, usually indicating that the containing element can be opened and closed.

Nicole Malandro

Graduate Student

Lab Phone

646-888-2322

I am part of the immunology program at Weill Cornell Graduate School. Due to natural safeguards to protect against autoimmunity tumor-self antigen specific T cells are eliminated from our immune repertoire and if present may be relatively scarce.  I am interested in how the precursor frequency of these tumor antigen specific CD4+ T cells shapes the effectiveness of an anti-tumor immune response.   To investigate this I have developed a model system in which precursor number can be manipulated in mice bearing implantable melanoma tumors through the adoptive transfer of tumor specific T cells of known specificity.