Tumors can be recognized by the immune system through their ability to make certain proteins that are not present in normal cells, called neoantigens. I am working to identify CD8+ T cells that recognize these neoantigens, in cancer patients using a combinatorial multimer technology. If we can identify relevant neoantigens, we may be able to augment tumor rejection by the immune system. In addition, I am working on a mouse model of oral cavity carcinoma to study the role of inflammation induced by bacteria in the mouth and the to response to immunotherapy.