More About The Jedd Wolchok Lab Minus iconIcon indicating subtraction, or that the element can be closed. Plus IconIcon indicating addition, or that the element can be opened. Arrow (down) icon.An arrow icon, usually indicating that the containing element can be opened and closed.

Sadna Budhu, PhD

Research Associate

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I developed a three-dimensional collagen-fibrin gel system to examine tumor specific T cell killing. Coupled with an equation (bt=b0e-kpt+gt) that accurately models T cell killing of melanoma cells, collagen-fibrin gels represent a quantitative model for assessing the cytolytic activity of antigen-specific T cells. My research focuses on quantitatively assessing the role of radiation, chemotherapy, immune modulation and cancer specific vaccines on the effector T cell responses to tumor antigens using breast cancer and melanoma as model systems.