More About The Marcel van den Brink Lab Minus iconIcon indicating subtraction, or that the element can be closed. Plus IconIcon indicating addition, or that the element can be opened. Arrow (down) icon.An arrow icon, usually indicating that the containing element can be opened and closed.

Scott James, MD, PhD

Assistant Attending Lv. 1

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University of Washington School of Medicine | Seattle, WA

Scott James received his MD and PhD from the University of Washington in Seattle where he studied aspects of chimeric antigen receptor-mediated T cell targeting related to target antigen topology and tissue expression. He subsequently completed internal medicine residency at University of Washington and joined the MSKCC hematology/oncology program. Upon completing his fellowship at MSKCC, he joined the Bone Marrow Transplantation Service as faculty member. 

Research Interests

Chimeric antigen receptor-modified T cells have demonstrated clinical successes in B cell malignancies and are currently being evaluated in other malignancies targeting novel antigens. I am interested in synthetic biology approaches to modify T cell behavior and function with the goal of improving the clinical efficacy and tissue selectivity of adoptive cellular immunotherapy. I additionally am interested in the application of synthetic biology approaches, including chimeric antigen receptors, to improve graft vs. leukemia/lymphoma responses while decreasing graft vs. host responses in the transplant setting. 


  • Parker Institute for Cancer Immunotherapy - Parker Bridge Scholar (2017-2020)
  • Amy Strelzer Manasevit Research Program Award (2017-2020)
  • ASCO Young Investigator Award (2016-2017)
  • T32 institutional training grant (Academic year 2015 – 2016)

My Projects