Memorial Hospital Research Laboratories

The Michael Roehrl Lab

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Research

Michael H. A. Roehrl, MD, PhD
Michael H. A. Roehrl, MD, PhD
Director, Precision Pathology Biobanking Center; Attending Pathologist

An overarching theme of my laboratory’s work is the experimental investigation of the network behavior of biological systems relevant to human disease using a variety of biochemical, biophysical, molecular biological, and systems modeling approaches. A primary focus is the biology of gastrointestinal solid tumors such as colorectal and pancreatic cancers.

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Research Projects

The Michael Roehrl Lab

Publications

Wang JY, Zhang W, Roehrl VB, Roehrl MW, Roehrl MH. An Autoantigen Atlas From Human Lung HFL1 Cells Offers Clues to Neurological and Diverse Autoimmune Manifestations of COVID-19. Front Immunol. 2022 Mar 24;13:831849. doi: 10.3389/fimmu.2022.831849. eCollection 2022.

Ogawa M, Tanaka A, Namba K, Shia J, Wang JY, Roehrl MH. Early-Stage Loss of GALNT6 Predicts Poor Clinical Outcome in Colorectal Cancer. Front Oncol. 2022 May 27;12:802548. doi: 10.3389/fonc.2022.802548. eCollection 2022.

Wang JY, Roehrl MW, Roehrl VB, Roehrl MH. A master autoantigen-ome links alternative splicing, female predilection, and COVID-19 to autoimmune diseases. J Transl Autoimmun. 2022;5:100147. doi: 10.1016/j.jtauto.2022.100147. Epub 2022 Feb 25.

Ogawa M, Tanaka A, Namba K, Shia J, Wang JY, Roehrl MHA. Tumor stromal nicotinamide N-methyltransferase overexpression as a prognostic biomarker for poor clinical outcome in early-stage colorectal cancer. Sci Rep. 2022 Feb 17;12(1):2767. doi: 10.1038/s41598-022-06772-w.

Omenn GS, Lane L, Overall CM, Paik YK, Cristea IM, Corrales FJ, Lindskog C, Weintraub S, Roehrl MHA, Liu S, Bandeira N, Srivastava S, Chen YJ, Aebersold R, Moritz RL, Deutsch EW. Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project. J Proteome Res. 2021 Dec 3;20(12):5227-5240. doi: 10.1021/acs.jproteome.1c00590. Epub 2021 Oct 20.

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People

Michael H. A. Roehrl, MD, PhD

Michael H. A. Roehrl, MD, PhD

Director, Precision Pathology Biobanking Center; Attending Pathologist

  • Physician-scientist Michael Roehrl studies gastrointestinal cancers and other solid tumors using proteomic, proteogenomic, and immunoproteomic approaches. We focus on risk-stratifying biomarkers and autoantigens in cancer and autoimmunity.
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Physician profile

Members

Masaki Maekawa

Research Scholar

Kei Namba

Research Fellow

Makiko Ogawa

Research Fellow

Atushi Tanaka

Research Fellow

Lab Affiliations

Open Positions

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Postdoctoral Fellows

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Michael H. A. Roehrl discloses the following relationships and financial interests:

  • Gerson Lehrman Group
    Provision of Services
  • Trans-Hit Biomarkers Inc.
    Provision of Services
  • Universal Diagnostics (UDX)
    Provision of Services

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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