More About The Michael Roehrl Lab Minus iconIcon indicating subtraction, or that the element can be closed. Plus IconIcon indicating addition, or that the element can be opened. Arrow (down) icon.An arrow icon, usually indicating that the containing element can be opened and closed.

Ongoing Projects

  • Development of high-resolution ultra-deep pan-proteomic profiling of primary human tumors by mass spectrometry
  • Integrated proteogenomic “big data” analyses of tumors using WGS/WES, RNA-Seq, and LC-MS datasets
  • Characterization of phosphoproteomic tumor signaling adaptation under targeted therapies (response vs. resistance)
  • Highly multiplexed quantitative protein biomarker assessment in clinical trials using LC-MS/MS
  • Elucidating the “antigen-ome” of autoreactive immunogenic tumor neoantigens in solid tumors