Michelle S. Bradbury: Publications


Thulborn KR, Lu A, Atkinson IC, Pauliah M, Beal K, Chan TA, Omuro A, Yamada J, Bradbury MS.  Residual Tumor Volume, Cell Volume Fraction, and Tumor Cell Kill During Fractionated Chemoradiation Therapy of Human Glioblastoma using Quantitative Sodium MR Imaging. Clinical Cancer. Research Published Online January 4th , 2019. Doi: 10.1158/1078-0432.CCR-18-2079. 

Chen F, Ma K, Madajewski B, Zhuang L, Zhang L, Rickert K, Marelli M, Yoo B, Turker MZ, Overholtzer M, Quinn TP, Gonen M, Zanzonico P, Tuesca A, Bowen MA, Norton L, Subramony JA, Wiesner U, Bradbury MS. Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer. Nat Commun. 9(1):4141, 1-11, 2018.

Chen F, Zhang X, Ma K, Madajewski B, Benezra M, Zhang L, Phillips E, Turker MZ, Gallazzi F, Penate-Medina O, Overholtzer M, Pauliah M, Gonen M, Zanzonico P, Wiesner U, Bradbury MS, Quinn TP.  Melanocortin-1 Receptor-Targeting Ultrasmall Silica Nanoparticles for Dual-Modality Human Melanoma Imaging.  ACS Appl Mater Interfaces.10 (5):4379-4393, 2018.  

Hartshorn CM, Bradbury MS, Lanza GM, Nel AE, Rao J, Wang AZ, Wiesner UB, Yang L, Grodzinski P. Nanotechnology Strategies To Advance Outcomes in Clinical Cancer Care. ACS Nano. 12(1):24-43, 2018.

Chen F, Ma K, Benezra M, Zhang L, Cheal SM, Phillips E, Yoo B, Pauliah M, Overholtzer M, Zanzonico P, Sequeira S, Gonen M, Quinn T, Wiesner U, Bradbury MS.  Cancer-Targeting Ultrasmall Silica Nanoparticles for Clinical Translation: Physicochemical Structure and Biological Property Correlations.  Chem Mater. 29(20):8766-8779, 2017.

Chen F, Ma K, Zhang L, Madajewski B, Zanzonico P, Sequeira S, Gonen M, Wiesner U, Bradbury MS. Target-or-Clear Zirconium-89 Labeled Silica Nanoparticles for Enhanced Cancer-Directed Uptake in Melanoma: A Comparison of Radiolabeling Strategies.  Chem Mater. 29(19):8269-8281, 2017.

Kim SE, Zhang L, Ma K, Gao M, Jiang X, Monette S, Mohan P, Gonen M, Zanzonico P, Quinn T, Wiesner U, Overholtzer M*, and Bradbury MS* (*co-senior authors).  Ultrasmall Nanoparticles Induce Ferroptosis of Nutrient-Deprived Cancer Cells and Suppress Tumor Growth Nat. Nanotech. (11):977-985, 2016. 

Bradbury MS, Pauliah M, P. Zanzonico, Wiesner U, and Patel S. Intraoperative mapping of SLN metastases using a clinically translated ultrasmall silica nanoparticles. Wiley Interdiscip Rev Nanomed Nanobiotechnol., 2015.

Yoo B, Ma K, Zhang L, Burns A, Sequeira S, Mellinghoff I, Brennan C, Wiesner U* and Bradbury MS* (*co-senior authors).  Ultrasmall Dual-Modality Nanoparticle Drug Conjugates: Design, Synthesis, and Characterization. Bioorg Med Chem. 23: 7119-30, 2015. 

Benezra M, Phillips E, Overholtzer M, Zanzonico P, Tuominin E, Wiesner U, and Bradbury MS. Ultrasmall Integrin-Targeted Silica Nanoparticles Modulate Signaling Events and Cellular Processes in a Concentration-Dependent Manner. Small. 11: 1721–1732, 2015.

Suteewong T, Ma K, Drews J, Werner-Zwanziger U, Wiesner U, Bradbury MS. Highly Fluorescent Sub 40-nm Aminated Mesoporous Silica Nanoparticles. J. Sol-Gel. Sci. Technol., 74:32–38, 2015.

Gabizon A, Bradbury MS, Bedian V, Prabhakar U, Zamboni W, Libutti S, and Grodzinski P.  Cancer nanomedicines- crossing the chasm. Lancet. 384: 2175-2176, 2014.

Phillips E, Penate-Medina O, Zanzonico PB, Carvajal RD, Mohan P, Ye Y, Humm J, Kaliagian H, Schöder H, Strauss W, Larson SM, Wiesner U, and Bradbury MS. Clinical Translation of an Ultrasmall Optical Hybrid Nanoparticle Probe. Sci. Transl. Med., 6: 260ra149, 2014.

Suteewong T, Sai H, Hovden R, Muller D, Bradbury MS, Gruner S, Wiesner U. Multicompartment Mesoporous Silica Nanoparticles with Branched Shapes: An Epitaxial Growth Mechanism. Science. 340: 337–341, 2013.

Bradbury MS, Phillips E, Montero P, Cheal S, Stambuk H, Durack J, Sofocleous CT, Meester RJC, Wiesner U, and Patel S. Clinically-Translated Silica Nanoparticles as Dual-Modality Cancer-Targeted Probes for Image-Guided Surgery and Interventions. Integr Biol. 5: 74 – 86, 2013.

Suteewong T, Sai H, Bradbury MS, Estroff L, Gruner S, Wiesner U. Synthesis and Formation Mechanism of Aminated Mesoporous Silica Nanoparticles. Chem Mater. 24: 3895-3905, 2012.

Benezra M*, Penate-Medina O*, Zanzonico P, Schaer D, Ow H, Burns A, De Stanchina E, Longo V, Herz E, Iyer S, Wolchok J, Larson S, Wiesner U, and Bradbury MS. Multimodal Silica Nanoparticles are Effective Cancer Targeted Probes in a Model of Human Melanoma. J Clin Invest. 121:2768-2780, 2011 (*co-first authors).

Penate Medina O, Haikola M, Tahtinen M, Simpura I, Kaukinen S, Valtanen H, Zhu Y, Wei C, Reunanen J, Nurminen T, Smith-Jones P, Bradbury M, Larson S, Kairemo K. Liposomal tumor targeting in drug delivery and imaging using MMP-2 and MMP-9 binding ligands. J Drug Delivery. 2011: 1-9, 2011.

Suteewong T, Sai H, Cohen R, Wang S, Bradbury M, Baird B, Gruner S, and Wiesner, U. Highly Aminated Mesoporous Silica Nanoparticles with Cubic Pore Structure. J. Am. Chem. Soc., 133: 172-175, 2011.

Suteewong T, Sai H, Lee J, Bradbury M, Hyeon T, Gruner S, and Wiesner U. Ordered Mesoporous Silica Nanoparticles with and without Embedded Iron Oxide Nanoparticles: Structure Evolution during Synthesis. J. Mater. Chem. 20: 7807-7814, 2010.

Burns A, Vider J, Ow H, Herz E, Penate-Medina O, Baumgart M, Larson S, Wiesner U, and Bradbury MS. Fluorescent Silica Nanoparticles with Efficient Urinary Excretion for Nanomedicine. Nano Letters. 9: 442-448, 2009.

Books, book chapters and reviews

Chen MY and Bradbury MS. Scope of Diagnostic Imaging. In: Chen MYM, Pope TL, and Ott DJ, eds.  Basic Radiology. New York: McGraw-Hill, 2004:1-12.

Bradbury MS and Williams DW. The Brain and Its Coverings. In: Chen MYM, Pope TL, and Ott DJ, eds. Basic Radiology. New York: McGraw-Hill, 2004:317-351.

Hricak HH, Akin O, Bradbury MS, Liberman L, Schwartz L, and Larson S. Advanced Imaging Methods. In: DeVita VT, Hellman S, and Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 7th ed. Philadelphia:  Lippincott Williams & Wilkins, 2004:1-29.

Bradbury MS and Gutin PH. Associations among magnetic resonance spectroscopy, apparent diffusion coefficients, and image-guided histopathology [Letter]. Neurosurgery. 2004; 54(5):1118-1119.

Bradbury MS and Hricak HH. Molecular Magnetic Resonance Imaging in Oncology: Future Directions. In: Martin DR, ed. MR Imaging Clinics of North America. Philadelphia:  W.B. Saunders Co, 2005;225-240.

Bradbury MS and Gutin PH. The potential of ferumoxytol nanoparticle magnetic resonance imaging, perfusion, and angiography in central nervous system malignancy: A pilot study [Letter]. Neurosurgery. 2007; 60(4):601-612.

Bradbury MS, Hricak HH, and Heath JR. Systems Biology and Nanotechnology: Linking Cancer Biology and Imaging. In: Reiser MF, Semmler W, and Hricak H, eds. Magnetic Resonance Tomography. Berlin and Heidelberg: Springer-Verlag, November 2007.

Zapadka ME, Bradbury MS, and Williams DW. The Brain and Its Coverings. In: Chen MYM, Pope TL, and Ott DJ, eds. Basic Radiology. 2nd ed. New York: McGraw-Hill, 2010

Bradbury MS, The Role of Molecular Imaging in Personalized Medicine. In: Faro S and Mohamed FB, eds. Functional Neuroradiology: Principles and Clinical Applications. Springer, 2011.

Bradbury MS, Mohan Pauliah, and Wiesner U. Ultrasmall Fluorescent Silica Nanoparticles as Intraoperative Imaging Tools for Cancer Diagnosis and Treatment. In: Fong Y and Lewis J, (Editors). The Modern Operating Room: Changing Role of Imaging and Visualization in Surgery. Springer, 2014.

Bradbury MS. First-in-human Molecular Targeting and Cancer Imaging using Ultrasmall Dual-Modality C dots.  In:  R. Bawa, G. Audette and I. Rubinstein. (Editors): Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy and Clinical Applications, Chapter 19, Pan Stanford Publishing, Singapore, 2015.