The Philip Kantoff Lab

My laboratory focuses on the molecular understanding of the highly variable phenotypic spectrum of prostate cancer. We take clinical observations and generate hypotheses that are initially tested in prostate cancer cell lines and then validated in patient specimens from hospital-based and large population-based cohorts. We use multiple approaches including epidemiology and molecular biology. Our primary areas of broad interest are the genetic epidemiology of prostate cancer, resistance mechanisms to therapy, non-coding RNAs and their role in prostate cancer, and hormone transporters.