The Prasad Jallepalli Lab

Our laboratory is interested in how human cells accurately duplicate and transmit their chromosomes during each round of division.

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Pictured: Prasad Jallepalli

Prasad Jallepalli, MD, PhD



Research Focus

Molecular biologist Prasad Jallepalli studies the mechanisms that ensure accurate chromosome transmission in human cells.


MD, PhD, Johns Hopkins University School of Medicine

Lab Members


  • M.E. Burkard, C.L. Randall, S. Larochelle, C. Zhang, K.M. Shokat, R.P. Fisher, and P.V. Jallepalli. Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells.  Proc. Natl. Acad. Sci. USA 104, 4383-4388 (2007).
  • M.E. Burkard, J. Maciejowski, V. Rodriguez-Bravo, M. Repka, D.M. Lowery, K.R. Clauser, C. Zhang, K.M. Shokat, S.A. Carr, M.B. Yaffe, and P.V. Jallepalli.  Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.  PLoS Biol. 7, e1000111 (2009).
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Selected Achievements

  • Phi Beta Kappa, Harvard University (1992)
  • M.D./Ph.D. Fellow, Medical Scientist Training Program, Johns Hopkins University (1992-1999)
  • Postdoctoral Fellow, Damon Runyon Cancer Foundation (1999-2002)
  • Scholar, V Foundation for Cancer Research (2003)
  • Frederick R. Adler Chair for Junior Faculty (2003-2007)
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  • Pew Scholar in the Biomedical Sciences (2003-2007)
  • Louise & Allston Boyer Young Investigator Award (2008)
  • Research Scholar, American Cancer Society (2008-2011)