Postdoctoral positions are available in the research group of Stephen Long at Memorial Sloan Kettering Cancer Center in New York City to study eukaryotic ion channels and membrane enzymes. We use a combination of cryo-electron microscopy, X-ray crystallography, electrophysiology, and other functional assays to delve deep into the molecular mechanisms of these membrane proteins. For examples, see Nature 516, 213-8 (2014), J Biol Chem. 289, 26007-20 (2014), Science 338, 1308-13 (2012), and Science 335, 432-6 (2012).
Our group is part of the Structural Biology Program at MSKCC, which contains an outstanding cohort of interactive scientists, and is strengthened by a community of nearby colleagues at the Rockefeller University, Weill Cornell Medical College, and the New York Structural Biology Center.
The laboratory is well funded and well equipped with access to state-of-the-art facilities. Major facilities include routine access to the Advanced Photon Source for X-ray diffraction experiments, MSKCC’s newly purchased Titan KRIOS microscope for cryo-EM experiments, on-site high performance computing, and cryo-EM resources at the nearby New York Structural Biology Center.
MSKCC is located on the upper east side of Manhattan, which is a lovely area to live and work. Subsidized housing is available for postdocs and their families and daycare is available for postdocs with young children. Read more about postdoctoral life.
Successful candidates will be passionate about science, creative, highly motivated, eager to learn, and enjoy working independently as well as in a collaborative environment. Candidates should be trained in biochemistry and structural biology using cryo-electron microscopy or X-ray crystallography, or trained in biochemistry and electrophysiology. Scientists with extensive experience in single particle cryo-EM, X-ray crystallography, or electrophysiology who are eager to study ion channels or membrane enzymes at a deep level and who would like to augment their skill set are encouraged to apply. The positions require excellent communication skills and fluency in spoken and written English. Candidates should have obtained their PhD within the last 3 years or will complete their PhD soon. Candidates are expected to have at least one published or upcoming first author paper. Alumni from the laboratory have been well positioned for their future careers.
Please send your application (as a single pdf document) including cover letter, brief statement of prior research experience and research interests, CV, and contact information for three references to Longs@mskcc.org.