Our laboratory uses a combination of structural and functional approaches to elucidate the mechanisms of eukaryotic ion channels and membrane-embedded enzymes. The proteins that we study have important biological roles and are implicated in diseases including cardiac arrhythmia, immune disorders, and cancer.

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Pictured: Stephen B. Long, PhD

Stephen B. Long, PhD

Associate Professor

Research Focus

Stephen Long studies the mechanisms of ion channels and enzymatic membrane proteins.


PhD, Duke University


  • Veronica K. Dickson, Leanne Pedi, Stephen B. Long.  Structure and insights into the function of a Ca2+-activated Cl− channel.  Nature. doi:10.1038/nature13913.  Published online 22 October 2014. (Abstract | Atomic Coordinates)
  • Melinda M. Diver and Stephen B. Long.  Mutational Analysis of the Integral Membrane Methyltransferase ICMT Reveals Potential Substrate Binding Sites. J Biol Chem. 2014. Sep 19;289(38):26007-20.  Epub 2014 Jul 24 (Abstract)
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