This laboratory is taking a biochemical approach to four problems in nucleic acid metabolism: the coordination of eukaryotic mRNA synthesis and processing, the structure and function of eukaryotic type I DNA topoisomerases, DNA damage recognition and repair by DNA ligases, and the mechanisms and biological roles of RNA repair enzymes.

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The Stewart Shuman Lab

Stewart Shuman, MD, PhD


Research Focus

Molecular biologist Stewart Shuman studies mechanisms and structures of the mRNA cap-forming enzymes and the means by which capping is coupled to transcription.


MD, PhD, Albert Einstein College of Medicine