The goal of my research is to understand the mechanisms and structures of enzymes that perform and regulate essential nucleic acid transactions. My research integrates diverse experimental approaches (including virology, biochemistry, structural biology, and genetics) and applies them to model systems ranging from viruses to bacteria to fungi to mammalian cells. An explicit aim is to identify novel enzymatic targets for treatment of human diseases.
Stewart Shuman, M.D., Ph.D.
American Cancer Society Research Professor
Research FocusThe goal of my research is to understand the mechanisms and structures of enzymes that perform and regulate essential nucleic acid transactions.
- B.A. Biology (1976) Wesleyan University
- Ph.D. Molecular Biology (1983) Albert Einstein College of Medicine
- M.D. (1981) Albert Einstein College of Medicine
- Changela A, Ho CK, Martins A, Shuman S, Mondragon A. (2001) Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme. EMBO J. 2001;20:2575-2586.
- Krogh BO, Shuman S. (2002) A poxvirus-like type IB topoisomerase family in bacteria. Proc Natl Acad Sci USA. 2002;99:1853-1858.
- Member of the American Academy of Arts and Sciences (2015)
- Fellow of the American Academy of Microbiology (2013)
- NIH MERIT Award (2007)
- American Cancer Society Research Professor (2005 - )
- American Society for Virology, Wolfgang Joklik Lectureship (2004)
- Burroughs Wellcome Fund Award - New Initiatives in Malaria Research (2001-03)
- Simon H. Rifkind Chair, Sloan-Kettering Institute (1999 - )
- American Cancer Society Faculty Research Award (1994-99)
- Pew Scholar (1990-94)
- American Cancer Society Junior Faculty Research Award (1989-92)
- Alpha Omega Alpha (1982)
- Phi Beta Kappa (1975)