The Chan lab focuses on cancer genomics and the drivers of response to cancer therapeutics. We are seeking a highly motivated candidate with a background in molecular/cellular biology to work at the interface of cancer biology and cancer genomics. Some immunology experience is welcome.
The successful candidate will work on the characterization of human cancers, perform experiments functionally characterizing tumor suppressor genes and oncogenes in vitro and in vivo, and carry out analyses linking findings in the tumor genome to patient outcomes.
Potential projects include but are not limited to examination of multi-omic datasets of cancer types treated with immunotherapy, investigating tumor suppressor genes, developing new immunocompetent mouse models, and immunologic interrogations of checkpoint blockade, combination therapies, and neoantigen screens in patient tumors and model systems.
The Chan Laboratory, together with the adjoining Immunogenomics and Precision Oncology Platform (IPOP), together comprise a dynamic group of over 20 scientists working collaboratively across the spectrum of cancer research, from basic molecular genetics, tumor immunology, mouse modeling, to computational biology and bioinformatics.
Approaches utilized include sequencing of exomes, transcriptomes, and T cell repertoires, as well as neoantigen immunogenicity screens, molecular cloning, biochemistry, and mouse models.
Applicants should hold a PhD and/or MD degree and have strong laboratory and analytical skills. Significant experience in molecular biology is required. Experience in immunology and/or basic genomics analysis is helpful. Good communication and organizational skills are a must.
Memorial Sloan Kettering Cancer Center is an equal opportunity employer with a strong commitment to enhancing the diversity of its faculty and staff. Women and applicants from diverse racial, ethnic and cultural backgrounds are encouraged to apply.