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The focus of our research is to understand the global genetic determinants of cancer development and therapeutic response. We primarily utilize data generated by next-generation sequencing technologies to study genomic mutations, copy number alterations, structural variations, and transcriptome changes, which together provide a molecular profile of individual tumors.

We collaborate closely with clinical investigators and researchers to integrate molecular and clinical information so as to identify molecular determinants of clinical phenotypes, thereby allowing more precise stratification of patient populations and targeting of cancer therapeutics.

Pictured: William Lee

William Lee, PhD

Research Focus

Computational biologist William Lee focuses on the application of high-throughput sequencing technologies for cancer biomarker discovery and diagnostics.