Research Labs

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20 Faculty Members found

Omar Abdel-Wahab, MD

Human Oncology & Pathogenesis Program

Physician-scientist Omar Abdel-Wahab studies the functional genomics of hematopoietic malignancies.

The Omar Abdel-Wahab Lab

Renier J. Brentjens, MD, PhD

Human Oncology & Pathogenesis Program

Physician-scientist Renier Brentjens develops novel immunotherapies for leukemias and lymphomas.

The Renier Brentjens Lab

Bayard Clarkson, MD

Molecular Pharmacology Program

Chemical biologist Bayard Clarkson focuses on the development of targeted therapies aimed at cancer stem cells.

Kristian Helin, PhD

Cell Biology Program

Cancer biologist Kristian Helin studies how genetic and epigenetic mechanisms affect transcription and cell-fate decisions, and how their deregulation contributes to cancer.

Kristian Helin Lab

Katharine C. Hsu, MD, PhD

Human Oncology & Pathogenesis Program

Physician-scientist Katharine Hsu studies the biology of human natural killer cells and how they contribute to disease processes.

The Katharine Hsu Lab

Andrew M. Intlekofer, MD, PhD

Human Oncology & Pathogenesis Program

Physician-scientist Andrew Intlekofer investigates why cancer cells depend on specific pathways of nutrient metabolism.

Andrew Intlekofer Lab Group

Alex Kentsis, MD, PhD

Molecular Pharmacology Program

Cancer biologist and pediatric oncologist Alex Kentsis leads research in the functional proteomics and molecular pharmacology of refractory childhood cancers.

The Alex Kentsis Lab

Michael G. Kharas, PhD

Molecular Pharmacology Program

Cancer biologist Michael Kharas studies RNA regulators of self-renewal in both normal and leukemic hematopoiesis.

Michael Kharas lab

Ross L. Levine, MD

Human Oncology & Pathogenesis Program

  1. Mechanisms of genetic and epigenetic cooperativity  which drive myeloid transformation
  2. Elucidating and modeling evolution from hematopoietic stem/progenitor cells to clonal hematopoiesis and then to myeloid malignancies
  3. Identification and credentialing novel therapeutic dependencies in myeloid malignancies

The Levine Lab

Paul A. Marks, MD

Cell Biology Program

Cell biologist Paul Marks focuses on the study of agents that selectively target histone deacetylases and cause transformed cell growth arrest, terminal differentiation, apoptosis, and/or cell death.